Development of Co-hemin MOF/chitosan composite based biosensor for rapid detection of lactose
- Authors
- Choi, Han Suk; Yang, Xiaoguang; Liu, Guicheng; Kim, Dong Sup; Yang, Ji Hyun; Lee, Ju Hun; Han, Sung Ok; Lee, Jinyoung; Kim, Seung Wook
- Issue Date
- Aug-2020
- Publisher
- ELSEVIER
- Keywords
- Electrochemical b osensor; Co-hemin; Metal organic frameworks; Cellobiose dehydrogenase; Lactose
- Citation
- JOURNAL OF THE TAIWAN INSTITUTE OF CHEMICAL ENGINEERS, v.113, pp.1 - 7
- Indexed
- SCIE
SCOPUS
- Journal Title
- JOURNAL OF THE TAIWAN INSTITUTE OF CHEMICAL ENGINEERS
- Volume
- 113
- Start Page
- 1
- End Page
- 7
- URI
- https://scholar.korea.ac.kr/handle/2021.sw.korea/54230
- DOI
- 10.1016/j.jtice.2020.07.021
- ISSN
- 1876-1070
- Abstract
- An electrochemical biosensor containing Co-hemin metal organic frameworks (Co-hemin MOF)/chitosan composite and cellobiose dehydrogenase (CDH) was developed for lactose dectection. The formation of the Co-hemin MOF was verified by scanning electron microscopy, Fourier transform infrared spectroscopy, UV-vis absorption spectroscopy and electrochemical techniques. The Co-hemin MOF/chitosan composite exhibited outstanding electrochemical performance on lactose detection with high sensitivity (102.3 mu A mM(-1) cm(-2)) and fast response (5 s). More importantly, the lower determination limit of 4 mM and the broad linear ranges of 10 to 100 mM were obtained to detect lactose. With broad linear ranges, the feasibility of dairy application of the biosensor based on Co-hemin MOF electrode was demonstrated in this study. (C) 2020 Taiwan Institute of Chemical Engineers. Published by Elsevier B.V. All rights reserved.
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Collections - Graduate School > Department of Biotechnology > 1. Journal Articles
- College of Engineering > Department of Chemical and Biological Engineering > 1. Journal Articles
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