Glucose oxidase-copper hybrid nanoflowers embedded with magnetic nanoparticles as an effective antibacterial agent
DC Field | Value | Language |
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dc.contributor.author | Lee, Inseon | - |
dc.contributor.author | Cheon, Hong Jae | - |
dc.contributor.author | Adhikari, Manab Deb | - |
dc.contributor.author | Tai Duc Tran | - |
dc.contributor.author | Yeon, Kyung-Min | - |
dc.contributor.author | Kim, Moon Il | - |
dc.contributor.author | Kim, Jungbae | - |
dc.date.accessioned | 2021-08-30T19:16:38Z | - |
dc.date.available | 2021-08-30T19:16:38Z | - |
dc.date.created | 2021-06-18 | - |
dc.date.issued | 2020-07-15 | - |
dc.identifier.issn | 0141-8130 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/54389 | - |
dc.description.abstract | Bacterial contamination causes various problems ranging from bacterial infection to biofouling. As an effective and non-toxic agent for bacterial de-contamination, glucose oxidase (GOx)-copper hybrid nanoflowers embedded with amine-functionalized magnetic nanoparticles (NH2-MNPs), called 'MNP-GOx NFs', are developed. Positively-charged NH2-MNPs and negatively- charged GOx molecules are first interacted via electrostatic attraction which can be controlled by changing the buffer pH, and the follow-up addition of copper(II) sulfate leads to blooming of nanoflowers (MNP-GOx NFs) after incubation at room temperature for 3 days. MNP-GOx NFs show effective antibacterial activity by generating H2O2 from GOx-catalyzed glucose oxidation. For example, 99.9% killings of Staphylococcus aureus and Escherichia coli are achieved after 3 h treatment of 10(6)/mL cells with 0.2 and 3.0 mg/mL MNP-GOx NFs, respectively, revealing that Gram-positive S. aureus with mono-layer membrane system is more vulnerable to the treatment of MNP-GOx NFs than Gram-negative E. coli with two-layer membrane system. MNP-GOx NFs can maintain 97% of bactericidal activity even after recycled uses by magnetic separation for eight times iterative bacterial killings. Finally, MNP-GOx NFs are employed for the fabrication of antibacterial gauzes. MNP-GOx NFs have also opened up a great potential for their applications in biosensors, biofuel cells and bioconversion as well as bacterial de-contamination. (C) 2019 Elsevier B.V. All rights reserved. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | ELSEVIER | - |
dc.subject | HYDROGEN-PEROXIDE | - |
dc.subject | FACILE SYNTHESIS | - |
dc.subject | IMMOBILIZATION | - |
dc.subject | SURFACES | - |
dc.subject | ACYLASE | - |
dc.subject | CHLOROPEROXIDASE | - |
dc.subject | LYSOSTAPHIN | - |
dc.subject | BIOSENSOR | - |
dc.subject | MEMBRANE | - |
dc.subject | STRATEGY | - |
dc.title | Glucose oxidase-copper hybrid nanoflowers embedded with magnetic nanoparticles as an effective antibacterial agent | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Kim, Jungbae | - |
dc.identifier.doi | 10.1016/j.ijbiomac.2019.11.129 | - |
dc.identifier.scopusid | 2-s2.0-85075899016 | - |
dc.identifier.wosid | 000536122500157 | - |
dc.identifier.bibliographicCitation | INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, v.155, pp.1520 - 1531 | - |
dc.relation.isPartOf | INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES | - |
dc.citation.title | INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES | - |
dc.citation.volume | 155 | - |
dc.citation.startPage | 1520 | - |
dc.citation.endPage | 1531 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Biochemistry & Molecular Biology | - |
dc.relation.journalResearchArea | Chemistry | - |
dc.relation.journalResearchArea | Polymer Science | - |
dc.relation.journalWebOfScienceCategory | Biochemistry & Molecular Biology | - |
dc.relation.journalWebOfScienceCategory | Chemistry, Applied | - |
dc.relation.journalWebOfScienceCategory | Polymer Science | - |
dc.subject.keywordPlus | HYDROGEN-PEROXIDE | - |
dc.subject.keywordPlus | FACILE SYNTHESIS | - |
dc.subject.keywordPlus | IMMOBILIZATION | - |
dc.subject.keywordPlus | SURFACES | - |
dc.subject.keywordPlus | ACYLASE | - |
dc.subject.keywordPlus | CHLOROPEROXIDASE | - |
dc.subject.keywordPlus | LYSOSTAPHIN | - |
dc.subject.keywordPlus | BIOSENSOR | - |
dc.subject.keywordPlus | MEMBRANE | - |
dc.subject.keywordPlus | STRATEGY | - |
dc.subject.keywordAuthor | Enzyme-inorganic hybrid nanoflowers | - |
dc.subject.keywordAuthor | Glucose oxidase | - |
dc.subject.keywordAuthor | Antibacterial activity | - |
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