Detailed Information

Cited 0 time in webofscience Cited 0 time in scopus
Metadata Downloads

Propensity score-matched analysis of internal stent vs external stent for pancreatojejunostomy during pancreaticoduodenectomy: Japanese-Korean cooperative project

Authors
Kawai, ManabuYamaue, HirokiJang, Jin-YoungUesaka, KatsuhikoUnno, MichiakiNakamura, MasafumiFujii, TsutomuSatoi, SoheiChoi, Seong HoSho, MasayukiFukumoto, TakumiKim, Song CheolHong, Tae HoIzumo, WataruYoon, Dong SupAmano, RyosukePark, Sang-JaeChoi, Sae ByeolYu, Hee ChulKim, Joo SeopAhn, Young JoonKim, HongbeomAshida, RyoHirono, SeikoHeo, Jin SeokSong, Ki ByungPark, Joon SeongYamamoto, MasakazuShimokawa, ToshioKim, Sun-Whe
Issue Date
7월-2020
Publisher
ELSEVIER
Keywords
Pancreaticoduodenectomy; Internal stent; External stent; Pancreatic fistula
Citation
PANCREATOLOGY, v.20, no.5, pp.984 - 991
Indexed
SCIE
SCOPUS
Journal Title
PANCREATOLOGY
Volume
20
Number
5
Start Page
984
End Page
991
URI
https://scholar.korea.ac.kr/handle/2021.sw.korea/54862
DOI
10.1016/j.pan.2020.06.014
ISSN
1424-3903
Abstract
Background: Several studies comparing internal and external stents have been conducted with the aim of reducing pancreatic fistula after PD. There is still no consensus, however, on the appropriate use of pancreatic stents for prevention of pancreatic fistula. This multicenter large cohort study aims to evaluate whether internal or external pancreatic stents are more effective in reduction of clinically relevant pancreatic fistula after pancreaticoduodenectomy (PD). Methods: We reviewed 3149 patients (internal stent n = 1,311, external stent n = 1838) who underwent PD at 20 institutions in Japan and Korea between 2007 and 2013. Propensity score matched analysis was used to minimize bias from nonrandomized treatment assignment. The primary endpoint was the incidence of clinically relevant pancreatic fistula. This study was registered on the UMIN Clinical Trials Registry (UMIN000032402). Results: After propensity score matched analysis, clinically relevant pancreatic fistula occurred in more patients in the external stents group (280 patients, 28.7%) than in patients in the internal stents group (126 patients, 12.9%) (OR 2.713 [95% CI, 2.139-3.455]; P < 0.001). In subset analysis of a high-risk group with soft pancreas and no dilatation of the pancreatic duct, clinically relevant pancreatic fistula occurred in 90 patients (18.8%) in internal stents group and 183 patients (35.4%) in external stents group. External stents were significantly associated with increased risk for clinically relevant pancreatic fistula (OR 2.366 [95% CI, 1.753-3.209]; P < 0.001). Conclusion: Propensity score matched analysis showed that, regarding clinically relevant pancreatic fistula after PD, internal stents are safer than external stents for pancreaticojejunostomy. (c) 2020 IAP and EPC. Published by Elsevier B.V. All rights reserved.
Files in This Item
There are no files associated with this item.
Appears in
Collections
College of Medicine > Department of Medical Science > 1. Journal Articles

qrcode

Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.

Related Researcher

Researcher Choi, Sae Byeol photo

Choi, Sae Byeol
의과대학 (의학과)
Read more

Altmetrics

Total Views & Downloads

BROWSE