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Combining viscosity-restricted intramolecular motion and mitochondrial targeting leads to selective tumor visualization
- Authors
- Yu, Le; Zhang, Jun Feng; Li, Mingle; Jiang, Dewei; Zhou, Ying; Verwilst, Peter; Kim, Jong Seung
- Issue Date
- 21-6월-2020
- Publisher
- ROYAL SOC CHEMISTRY
- Citation
- CHEMICAL COMMUNICATIONS, v.56, no.49, pp.6684 - 6687
- Indexed
- SCIE
SCOPUS
- Journal Title
- CHEMICAL COMMUNICATIONS
- Volume
- 56
- Number
- 49
- Start Page
- 6684
- End Page
- 6687
- ISSN
- 1359-7345
- Abstract
- We report a novel fluorescent molecular conjugate,V-M1,enabling an accurate visualization of tumor tissues. The emission wavelength ofV-M1exceeds 650 nm, which is well within the near-infrared therapeutic window. Tumor accumulation of this cationic dye allows the visualization of cancerous cells as a function of mitochondrial viscosity.
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Collections - College of Science > Department of Chemistry > 1. Journal Articles
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