The Roles of CCR7 for the Homing of Memory CD8+T Cells into Their Survival Niches
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Choi, Hanbyeui | - |
dc.contributor.author | Song, Heonju | - |
dc.contributor.author | Jung, Yong Woo | - |
dc.date.accessioned | 2021-08-30T22:28:15Z | - |
dc.date.available | 2021-08-30T22:28:15Z | - |
dc.date.created | 2021-06-18 | - |
dc.date.issued | 2020-06 | - |
dc.identifier.issn | 1598-2629 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/55565 | - |
dc.description.abstract | Memory CD8+ T cells in the immune system are responsible for the removal of external Ags for a long period of time to protect against re-infection. Naive to memory CD8+ T cell differentiation and memory CD8+ T cell maintenance require many different factors including local environmental factors. Thus, it has been suggested that the migration of memory CD8+ T cells into specific microenvironments alters their longevity and functions. In this review, we have summarized the subsets of memory CD8+ T cells based on their migratory capacities and described the niche hypothesis for their survival. In addition, the basic roles of CCR7 in conjunction with the migration of memory CD8+ T cells and recent understandings of their survival niches have been introduced. Finally, the applications of altering CCR7 signaling have been discussed. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | KOREA ASSOC IMMUNOLOGISTS | - |
dc.subject | CHEMOKINE RECEPTOR CCR7 | - |
dc.subject | T-CELLS | - |
dc.subject | RESIDENT MEMORY | - |
dc.subject | HOMEOSTATIC PROLIFERATION | - |
dc.subject | EBI1-LIGAND CHEMOKINE | - |
dc.subject | FUNCTIONAL LIGAND | - |
dc.subject | LYMPHOID ORGANS | - |
dc.subject | STROMAL CELLS | - |
dc.subject | IN-VIVO | - |
dc.subject | EXPRESSION | - |
dc.title | The Roles of CCR7 for the Homing of Memory CD8+T Cells into Their Survival Niches | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Choi, Hanbyeui | - |
dc.contributor.affiliatedAuthor | Jung, Yong Woo | - |
dc.identifier.doi | 10.4110/in.2020.20.e20 | - |
dc.identifier.scopusid | 2-s2.0-85087430707 | - |
dc.identifier.wosid | 000546250100001 | - |
dc.identifier.bibliographicCitation | IMMUNE NETWORK, v.20, no.3 | - |
dc.relation.isPartOf | IMMUNE NETWORK | - |
dc.citation.title | IMMUNE NETWORK | - |
dc.citation.volume | 20 | - |
dc.citation.number | 3 | - |
dc.type.rims | ART | - |
dc.type.docType | Review | - |
dc.identifier.kciid | ART002606186 | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.description.journalRegisteredClass | kci | - |
dc.relation.journalResearchArea | Immunology | - |
dc.relation.journalWebOfScienceCategory | Immunology | - |
dc.subject.keywordPlus | CHEMOKINE RECEPTOR CCR7 | - |
dc.subject.keywordPlus | T-CELLS | - |
dc.subject.keywordPlus | RESIDENT MEMORY | - |
dc.subject.keywordPlus | HOMEOSTATIC PROLIFERATION | - |
dc.subject.keywordPlus | EBI1-LIGAND CHEMOKINE | - |
dc.subject.keywordPlus | FUNCTIONAL LIGAND | - |
dc.subject.keywordPlus | LYMPHOID ORGANS | - |
dc.subject.keywordPlus | STROMAL CELLS | - |
dc.subject.keywordPlus | IN-VIVO | - |
dc.subject.keywordPlus | EXPRESSION | - |
dc.subject.keywordAuthor | CD8-positive T-lymphocytes | - |
dc.subject.keywordAuthor | Immunologic memory | - |
dc.subject.keywordAuthor | Receptors | - |
dc.subject.keywordAuthor | CCR7 | - |
dc.subject.keywordAuthor | Cell movement | - |
dc.subject.keywordAuthor | Chemotaxis | - |
dc.subject.keywordAuthor | Immunotherapy | - |
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