Risk factors for primary lung cancer among never- smoking women in South Korea: a retrospective nationwide population-based cohort study
DC Field | Value | Language |
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dc.contributor.author | Ko, Yoon Ho | - |
dc.contributor.author | Kim, Seung Joon | - |
dc.contributor.author | Kim, Wan-Seop | - |
dc.contributor.author | Park, Chan Kwon | - |
dc.contributor.author | Park, Cheol-Kyu | - |
dc.contributor.author | Suh, Yang-Gun | - |
dc.contributor.author | Eom, Jung Seop | - |
dc.contributor.author | Cho, Sukki | - |
dc.contributor.author | Hur, Jae Young | - |
dc.contributor.author | Hwang, Sung Ho | - |
dc.contributor.author | Myong, Jun-Pyo | - |
dc.date.accessioned | 2021-08-31T01:06:02Z | - |
dc.date.available | 2021-08-31T01:06:02Z | - |
dc.date.created | 2021-06-19 | - |
dc.date.issued | 2020-05 | - |
dc.identifier.issn | 1226-3303 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/56083 | - |
dc.description.abstract | Background/Aims: We performed a large-scale, retrospective, nationwide, cohort study to investigate the risk factors for lung cancer among never-smoking Korean females. Methods: The study data were collected from a general health examination and questionnaire survey of eligible populations conducted between January 1, 2003 and December 31, 2004; the data were acquired from the tailored big data distribution service of the National Health Insurance Service. After a 1-year clearance period, 5,860,922 of 6,318,878 never-smoking female participants with no previous history of lung cancer were investigated. After a median follow-up of 11.4 years, 43,473 (0.74%) participants were defined as "newly diagnosed lung cancer". Results: After adjusting for all variables at baseline, the variables older age, lower body mass index (BMI), less exercise, frequent alcohol drinking, meat-based diet, rural residence, and previous history of cancer were associated with a higher incidence of lung cancer. Low BMI (< 18.5 kg/m(2): hazard ratio [HR], 1.33; 95% confidence interval [CI], 1.27 to 1.40) was a significant independent risk factor; as BMI decreased, HR increased. Negative associations between BMI and lung-cancer development were also observed after controlling for age (p for trend < 0.001). Drinking alcohol one to two times a week (HR, 1.25; 95% CI, 1.21 to 1.28) and eating a meat-based diet (HR, 1.08; 95% CI, 1.01 to 1.35) were associated with lung-cancer incidence. Conclusions: Modifiable baseline characteristics, such as BMI, exercise, alcohol consumption, and diet, are risk factors for lung-cancer development among never-smoking females. Thus, lifestyle modifications may help prevent lung cancer. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | KOREAN ASSOC INTERNAL MEDICINE | - |
dc.subject | BODY-MASS INDEX | - |
dc.subject | PESTICIDES | - |
dc.subject | ADDUCTS | - |
dc.subject | LEPTIN | - |
dc.subject | TISSUE | - |
dc.title | Risk factors for primary lung cancer among never- smoking women in South Korea: a retrospective nationwide population-based cohort study | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Hwang, Sung Ho | - |
dc.identifier.doi | 10.3904/kjim.2019.283 | - |
dc.identifier.scopusid | 2-s2.0-85084696188 | - |
dc.identifier.wosid | 000530244800021 | - |
dc.identifier.bibliographicCitation | KOREAN JOURNAL OF INTERNAL MEDICINE, v.35, no.3, pp.692 - 702 | - |
dc.relation.isPartOf | KOREAN JOURNAL OF INTERNAL MEDICINE | - |
dc.citation.title | KOREAN JOURNAL OF INTERNAL MEDICINE | - |
dc.citation.volume | 35 | - |
dc.citation.number | 3 | - |
dc.citation.startPage | 692 | - |
dc.citation.endPage | 702 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.identifier.kciid | ART002580411 | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.description.journalRegisteredClass | kci | - |
dc.relation.journalResearchArea | General & Internal Medicine | - |
dc.relation.journalWebOfScienceCategory | Medicine, General & Internal | - |
dc.subject.keywordPlus | BODY-MASS INDEX | - |
dc.subject.keywordPlus | PESTICIDES | - |
dc.subject.keywordPlus | ADDUCTS | - |
dc.subject.keywordPlus | LEPTIN | - |
dc.subject.keywordPlus | TISSUE | - |
dc.subject.keywordAuthor | Lung neoplasm | - |
dc.subject.keywordAuthor | Never-smoking women | - |
dc.subject.keywordAuthor | Risk factor | - |
dc.subject.keywordAuthor | Cohort studies | - |
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