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A fluorescent nanobiosensor for the facile analysis of m(6)A RNA demethylase activity

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dc.contributor.authorYim, Seo-Hee-
dc.contributor.authorCha, Hyung Jin-
dc.contributor.authorPark, Se-Jin-
dc.contributor.authorYim, Yeajee-
dc.contributor.authorWoo, Jae-Sung-
dc.contributor.authorMin, Dal-Hee-
dc.date.accessioned2021-08-31T01:49:29Z-
dc.date.available2021-08-31T01:49:29Z-
dc.date.created2021-06-19-
dc.date.issued2020-04-30-
dc.identifier.issn1359-7345-
dc.identifier.urihttps://scholar.korea.ac.kr/handle/2021.sw.korea/56264-
dc.description.abstractRNA demethylase has recently been known to be associated with cancer development but its selective inhibitors as anti-cancer agents have rarely been investigated to date. Herein, we have developed a fluorescent nanobiosensor which enables efficient quantitative analysis of RNA demethylase ALKBH5 activity and shows a high potential for robust inhibitor screening.-
dc.languageEnglish-
dc.language.isoen-
dc.publisherROYAL SOC CHEMISTRY-
dc.subjectMETTL3-METTL14 COMPLEX-
dc.subjectNUCLEAR-RNA-
dc.subjectALKBH5-
dc.subjectMOUSE-
dc.subjectASSAY-
dc.subjectEXPRESSION-
dc.subjectSUBSTRATE-
dc.subjectPLATFORM-
dc.titleA fluorescent nanobiosensor for the facile analysis of m(6)A RNA demethylase activity-
dc.typeArticle-
dc.contributor.affiliatedAuthorWoo, Jae-Sung-
dc.identifier.doi10.1039/c9cc10054g-
dc.identifier.scopusid2-s2.0-85084167004-
dc.identifier.wosid000530725500017-
dc.identifier.bibliographicCitationCHEMICAL COMMUNICATIONS, v.56, no.34, pp.4716 - 4719-
dc.relation.isPartOfCHEMICAL COMMUNICATIONS-
dc.citation.titleCHEMICAL COMMUNICATIONS-
dc.citation.volume56-
dc.citation.number34-
dc.citation.startPage4716-
dc.citation.endPage4719-
dc.type.rimsART-
dc.type.docTypeArticle-
dc.description.journalClass1-
dc.description.journalRegisteredClassscie-
dc.description.journalRegisteredClassscopus-
dc.relation.journalResearchAreaChemistry-
dc.relation.journalWebOfScienceCategoryChemistry, Multidisciplinary-
dc.subject.keywordPlusMETTL3-METTL14 COMPLEX-
dc.subject.keywordPlusNUCLEAR-RNA-
dc.subject.keywordPlusALKBH5-
dc.subject.keywordPlusMOUSE-
dc.subject.keywordPlusASSAY-
dc.subject.keywordPlusEXPRESSION-
dc.subject.keywordPlusSUBSTRATE-
dc.subject.keywordPlusPLATFORM-
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