A fluorescent nanobiosensor for the facile analysis of m(6)A RNA demethylase activity
- Authors
- Yim, Seo-Hee; Cha, Hyung Jin; Park, Se-Jin; Yim, Yeajee; Woo, Jae-Sung; Min, Dal-Hee
- Issue Date
- 30-4월-2020
- Publisher
- ROYAL SOC CHEMISTRY
- Citation
- CHEMICAL COMMUNICATIONS, v.56, no.34, pp.4716 - 4719
- Indexed
- SCIE
SCOPUS
- Journal Title
- CHEMICAL COMMUNICATIONS
- Volume
- 56
- Number
- 34
- Start Page
- 4716
- End Page
- 4719
- URI
- https://scholar.korea.ac.kr/handle/2021.sw.korea/56264
- DOI
- 10.1039/c9cc10054g
- ISSN
- 1359-7345
- Abstract
- RNA demethylase has recently been known to be associated with cancer development but its selective inhibitors as anti-cancer agents have rarely been investigated to date. Herein, we have developed a fluorescent nanobiosensor which enables efficient quantitative analysis of RNA demethylase ALKBH5 activity and shows a high potential for robust inhibitor screening.
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- There are no files associated with this item.
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Collections - Graduate School > Department of Life Sciences > 1. Journal Articles
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