Efficacy of a povidone-iodine foam dressing (Betafoam) on diabetic foot ulcer
- Authors
- Gwak, Heui C.; Han, Seung H.; Lee, Jinwoo; Park, Sejin; Sung, Ki-Sun; Kim, Hak-Jun; Chun, Dongil; Lee, Kyungmin; Ahn, Jae-Hoon; Kwak, Kyunghee; Chung, Hyung-Jin
- Issue Date
- 2월-2020
- Publisher
- WILEY
- Keywords
- Betafoam; diabetic foot ulcer; Medifoam; povidone-iodine; wound healing
- Citation
- INTERNATIONAL WOUND JOURNAL, v.17, no.1, pp.91 - 99
- Indexed
- SCIE
SCOPUS
- Journal Title
- INTERNATIONAL WOUND JOURNAL
- Volume
- 17
- Number
- 1
- Start Page
- 91
- End Page
- 99
- URI
- https://scholar.korea.ac.kr/handle/2021.sw.korea/57833
- DOI
- 10.1111/iwj.13236
- ISSN
- 1742-4801
- Abstract
- This study aimed to assess the efficacy of a new povidone-iodine (PVP-I) foam dressing (Betafoam) vs foam dressing (Medifoam) for the management of diabetic foot ulcers. This study was conducted between March 2016 and September 2017 at 10 sites in Korea. A total of 71 patients (aged >= 19 years) with type 1/2 diabetes and early-phase diabetic foot ulcers (Wagener classification grade 1/2) were randomised to treatment with PVP-I foam dressing or foam dressing for 8 weeks. Wound healing, wound infection, patient satisfaction, and adverse events (AEs) were assessed. The PVP-I foam and foam dressing groups were comparable in the proportion of patients with complete wound healing within 8 weeks (44.4% vs 42.3%, P = .9191), mean (+/- SD) number of days to complete healing (31.00 +/- 15.07 vs 33.27 +/- 12.60 days; P = .6541), and infection rates (11.1% vs 11.4%; P = 1.0000). Median satisfaction score (scored from 0 to 10) at the final visit was also comparable between groups (10 vs 9, P = .2889). There was no significant difference in AE incidence (27.8% vs 17.1%, P = .2836), and none of the reported AEs had a causal relationship with the dressings. The results of this study suggest that PVP-I foam dressing has wound-healing efficacy comparable with foam dressing, with no notable safety concerns. This study was funded by Mundipharma Korea Ltd and registered at (identifier NCT02732886).
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Collections - College of Medicine > Department of Medical Science > 1. Journal Articles
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