Parasympathetic predominance is a risk factor for future depression: A prospective cohort study
DC Field | Value | Language |
---|---|---|
dc.contributor.author | An, Hoyoung | - |
dc.contributor.author | Han, Ji Won | - |
dc.contributor.author | Jeong, Hyun-Ghang | - |
dc.contributor.author | Kim, Tae Hui | - |
dc.contributor.author | Lee, Jung Jae | - |
dc.contributor.author | Lee, Seok Bum | - |
dc.contributor.author | Park, Joon Hyuk | - |
dc.contributor.author | Kim, Ki Woong | - |
dc.date.accessioned | 2021-08-31T14:44:58Z | - |
dc.date.available | 2021-08-31T14:44:58Z | - |
dc.date.created | 2021-06-19 | - |
dc.date.issued | 2020-01-01 | - |
dc.identifier.issn | 0165-0327 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/58370 | - |
dc.description.abstract | Background: Changes in parasympathetic activity have been associated with depression; however, it is not well understood whether these changes are a result of depression, or represent a compensatory mechanism protecting against it. We examined the association of autonomic nervous system activity with the risk of depression in euthymic individuals and those with subsyndromal depression using heart rate variability (HRV) analysis. Methods: From a community-based longitudinal cohort, 464 subjects from the baseline assessment and 253 who completed the 5-year follow-up visit were included in the cross-sectional and prospective analyses, respectively. Linear regression analysis was used to investigate the association of HRV measures with the current and future GDS scores. Logistic regression analysis examined the effect of HRV on future risk of SSD. Results: Low-frequency power (LFN), high-frequency power (HFN), and the LFN/HFN ratio at the baseline assessment were associated with the GDS score at the 5-year follow-up assessment; however, they were not associated with the GDS score at the baseline assessment. High HFN indicated an increased risk of depression at the 5-year follow-up assessment in euthymic subjects (OR = 3.025, 95% CI = 1.184 - 7.726, p = 0.021). Limitations: HRV was not measured at the follow-up assessment and the interval between the assessments was comparatively long. Five-minute ECG recordings were used, and all participants were 65 years old or older. Conclusions: Parasympathetic predominance may precede the onset of depression in older adults. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | ELSEVIER | - |
dc.subject | HEART-RATE-VARIABILITY | - |
dc.subject | MYOCARDIAL-INFARCTION | - |
dc.subject | VAGAL TONE | - |
dc.subject | SYMPTOMS | - |
dc.subject | ADULTS | - |
dc.title | Parasympathetic predominance is a risk factor for future depression: A prospective cohort study | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Jeong, Hyun-Ghang | - |
dc.identifier.doi | 10.1016/j.jad.2019.09.015 | - |
dc.identifier.scopusid | 2-s2.0-85072223795 | - |
dc.identifier.wosid | 000490428300032 | - |
dc.identifier.bibliographicCitation | JOURNAL OF AFFECTIVE DISORDERS, v.260, pp.232 - 237 | - |
dc.relation.isPartOf | JOURNAL OF AFFECTIVE DISORDERS | - |
dc.citation.title | JOURNAL OF AFFECTIVE DISORDERS | - |
dc.citation.volume | 260 | - |
dc.citation.startPage | 232 | - |
dc.citation.endPage | 237 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | ssci | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Neurosciences & Neurology | - |
dc.relation.journalResearchArea | Psychiatry | - |
dc.relation.journalWebOfScienceCategory | Clinical Neurology | - |
dc.relation.journalWebOfScienceCategory | Psychiatry | - |
dc.subject.keywordPlus | HEART-RATE-VARIABILITY | - |
dc.subject.keywordPlus | MYOCARDIAL-INFARCTION | - |
dc.subject.keywordPlus | VAGAL TONE | - |
dc.subject.keywordPlus | SYMPTOMS | - |
dc.subject.keywordPlus | ADULTS | - |
dc.subject.keywordAuthor | Depression | - |
dc.subject.keywordAuthor | Biological markers | - |
dc.subject.keywordAuthor | Geriatric | - |
dc.subject.keywordAuthor | Parasympathetic nervous system | - |
dc.subject.keywordAuthor | Cardiovascular | - |
dc.subject.keywordAuthor | Heart-rate variability | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
(02841) 서울특별시 성북구 안암로 14502-3290-1114
COPYRIGHT © 2021 Korea University. All Rights Reserved.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.