Autoimmunity in microbiome-mediated diseases and novel therapeutic approaches
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Shin, Cheolmin | - |
dc.contributor.author | Kim, Yong-Ku | - |
dc.date.accessioned | 2021-08-31T22:42:02Z | - |
dc.date.available | 2021-08-31T22:42:02Z | - |
dc.date.created | 2021-06-19 | - |
dc.date.issued | 2019-12 | - |
dc.identifier.issn | 1471-4892 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/61370 | - |
dc.description.abstract | The microbiome mediates constant bidirectional communication with the host immune system in a delicate balance of inducing pathogenic infection or residing in the human body in a cornmensal state. Dysbiosis is a hallmark of several autoimmune and immune-mediated inflammatory diseases. Various pathways involved in microbiome-induced autoimmunity are activated when a genetic defect or microbial trigger is found in the inflammasome, neutrophil extracellular trap, or receptors for microbial sensitization in the innate immune system or when similar defects are present in T or B lymphocytes of the adaptive immune system. Regulating autoimmunity through microbiome modulation may be highly effective as a therapeutic intervention. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | ELSEVIER SCI LTD | - |
dc.subject | SEGMENTED FILAMENTOUS BACTERIA | - |
dc.subject | ARYL-HYDROCARBON RECEPTOR | - |
dc.subject | REGULATORY B-CELLS | - |
dc.subject | T-CELLS | - |
dc.subject | GUT MICROBIOTA | - |
dc.subject | INTESTINAL MICROBIOTA | - |
dc.subject | MODULATED METABOLITES | - |
dc.subject | SELECTION | - |
dc.subject | INNATE | - |
dc.subject | IGA | - |
dc.title | Autoimmunity in microbiome-mediated diseases and novel therapeutic approaches | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Shin, Cheolmin | - |
dc.contributor.affiliatedAuthor | Kim, Yong-Ku | - |
dc.identifier.doi | 10.1016/j.coph.2019.04.018 | - |
dc.identifier.scopusid | 2-s2.0-85065859725 | - |
dc.identifier.wosid | 000503086500017 | - |
dc.identifier.bibliographicCitation | CURRENT OPINION IN PHARMACOLOGY, v.49, pp.34 - 42 | - |
dc.relation.isPartOf | CURRENT OPINION IN PHARMACOLOGY | - |
dc.citation.title | CURRENT OPINION IN PHARMACOLOGY | - |
dc.citation.volume | 49 | - |
dc.citation.startPage | 34 | - |
dc.citation.endPage | 42 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Pharmacology & Pharmacy | - |
dc.relation.journalWebOfScienceCategory | Pharmacology & Pharmacy | - |
dc.subject.keywordPlus | SEGMENTED FILAMENTOUS BACTERIA | - |
dc.subject.keywordPlus | ARYL-HYDROCARBON RECEPTOR | - |
dc.subject.keywordPlus | REGULATORY B-CELLS | - |
dc.subject.keywordPlus | T-CELLS | - |
dc.subject.keywordPlus | GUT MICROBIOTA | - |
dc.subject.keywordPlus | INTESTINAL MICROBIOTA | - |
dc.subject.keywordPlus | MODULATED METABOLITES | - |
dc.subject.keywordPlus | SELECTION | - |
dc.subject.keywordPlus | INNATE | - |
dc.subject.keywordPlus | IGA | - |
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