Comparison of Two-Year Outcomes of Acute Myocardial Infarction Caused by Coronary Artery Spasm Versus that Caused by Coronary Atherosclerosis
- Authors
- Baek, Ju Yeol; Choi, Byoung Geol; Rha, Seung-Woon; Choi, Cheol Ung; Park, Chang Gyu; Seo, Hong Seog; Oh, Dong Joo; Ahn, Tae Hoon; Chang, Kiyuk; Chae, Shung-Chull; Hur, Seung Ho; Cha, Kwang-Soo; Choi, In-Ho; Kim, Hyo-Soo; Gwon, Hyeon Cheol; Kim, Young Jo; Oh, Seok Kyu; Chae, Jei Keon; Seong, In Whan; Hwang, Kyung-Kook; Kim, Chong Jin; Yoon, Jung-Han; Hwang, Jin Yong; Kim, Doo Il; Joo, Seung Jae; Jeong, Myung Ho
- Issue Date
- 15-11월-2019
- Publisher
- EXCERPTA MEDICA INC-ELSEVIER SCIENCE INC
- Citation
- AMERICAN JOURNAL OF CARDIOLOGY, v.124, no.10, pp.1493 - 1500
- Indexed
- SCIE
SCOPUS
- Journal Title
- AMERICAN JOURNAL OF CARDIOLOGY
- Volume
- 124
- Number
- 10
- Start Page
- 1493
- End Page
- 1500
- URI
- https://scholar.korea.ac.kr/handle/2021.sw.korea/61573
- DOI
- 10.1016/j.amjcard.2019.08.019
- ISSN
- 0002-9149
- Abstract
- The study compared the 2-year outcomes of patients diagnosed with acute myocardial infarction (AMI) triggered by coronary artery atherosclerosis and AMI caused by coronary artery spasm. A total of 36,797 patients in the Korea AMI Registry were grouped into 2 categories-(1) AMI due to coronary artery spasm without stenotic lesion (CAS-AMI, n = 484); and (2) AMI induced by coronary artery atherosclerosis (CAA-AMI, n = 36,313). The major clinical outcomes of the 2 groups were compared over a 2-year clinical follow-up period. Major adverse cardiac events (MACE) were defined as the composite of total death, nonfatal myocardial infarction, and repeat revascularization. The incidence of MACE (7.1% vs 11.1%; p = 0.007) and repeat revascularization (0.4% vs 4.2 %; p <0.001) in the CAS-AMI group were significantly lower than in the CAA-AMI group at 2 years. However, the incidence of total death and nonfatal myocardial infarction was similar in both the groups. Aborted cardiac arrest was strongly associated with 2-year mortality in the CAS-AMI group (hazard ratios 13.5, 95% confidence interval 5.34 to 34.15, p <0.001) The incidence of MACE in CAS-AMI patients was significantly lower than in the CAA-AMI group of patients up to 2 years due to the relatively lower rate of repeat revascularization in CAS-AMI patients. However, the incidence of total death or nonfatal myocardial infarction in CAS-AMI patients was not different from that of patients with CAA-AMI. (C) 2019 Elsevier Inc. All rights reserved.
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Collections - Graduate School > Department of Biomedical Sciences > 1. Journal Articles
- College of Medicine > Department of Medical Science > 1. Journal Articles
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