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Monoamine oxidase-A targeting probe for prostate cancer imaging and inhibition of metastasis

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dc.contributor.authorKim, Won Young-
dc.contributor.authorWon, Miae-
dc.contributor.authorSalimi, Abbas-
dc.contributor.authorSharma, Amit-
dc.contributor.authorLim, Jong Hyeon-
dc.contributor.authorKwon, Seung-Hae-
dc.contributor.authorJeon, Joo-Yeong-
dc.contributor.authorLee, Jin Yong-
dc.contributor.authorKim, Jong Seung-
dc.date.accessioned2021-08-31T23:06:48Z-
dc.date.available2021-08-31T23:06:48Z-
dc.date.created2021-06-18-
dc.date.issued2019-11-14-
dc.identifier.issn1359-7345-
dc.identifier.urihttps://scholar.korea.ac.kr/handle/2021.sw.korea/61591-
dc.description.abstractMitochondrial enzyme monoamine oxidase (MAO-A) is known to be overexpressed in prostate cancer (PCa) cells. Herein, we have developed a two-photon probe (PCP-1) for selectively targeting and imaging the MAO-A in PCa. Supported by enzymatic docking and in vitro experiments, PCP-1 showed efficiency to visualize MAO-A overexpressing cells and inhibit their growth and metastasis potential.-
dc.languageEnglish-
dc.language.isoen-
dc.publisherROYAL SOC CHEMISTRY-
dc.subjectANTIGEN-
dc.titleMonoamine oxidase-A targeting probe for prostate cancer imaging and inhibition of metastasis-
dc.typeArticle-
dc.contributor.affiliatedAuthorWon, Miae-
dc.contributor.affiliatedAuthorKim, Jong Seung-
dc.identifier.doi10.1039/c9cc07009e-
dc.identifier.scopusid2-s2.0-85074306673-
dc.identifier.wosid000495086800012-
dc.identifier.bibliographicCitationCHEMICAL COMMUNICATIONS, v.55, no.88, pp.13267 - 13270-
dc.relation.isPartOfCHEMICAL COMMUNICATIONS-
dc.citation.titleCHEMICAL COMMUNICATIONS-
dc.citation.volume55-
dc.citation.number88-
dc.citation.startPage13267-
dc.citation.endPage13270-
dc.type.rimsART-
dc.type.docTypeArticle-
dc.description.journalClass1-
dc.description.journalRegisteredClassscie-
dc.description.journalRegisteredClassscopus-
dc.relation.journalResearchAreaChemistry-
dc.relation.journalWebOfScienceCategoryChemistry, Multidisciplinary-
dc.subject.keywordPlusANTIGEN-
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