Differences in bone density on chest CT according to smoking status in males without chronic obstructive lung disease
- Authors
- Kim, Cherry; Kim, Soriul; Lee, Ki Yeol; Kim, Nan Hee; Kang, Eun-Young; Oh, Yu-Whan; Shin, Chol
- Issue Date
- 2-9월-2019
- Publisher
- NATURE PUBLISHING GROUP
- Citation
- SCIENTIFIC REPORTS, v.9
- Indexed
- SCIE
SCOPUS
- Journal Title
- SCIENTIFIC REPORTS
- Volume
- 9
- URI
- https://scholar.korea.ac.kr/handle/2021.sw.korea/62924
- DOI
- 10.1038/s41598-019-46830-4
- ISSN
- 2045-2322
- Abstract
- The goals of this study were to determine whether bone density measured using CT (CTBD) can show significant differences in bone loss according to smoking status and pack-years, and to examine the correlation between CTBD and bone mineral density when measured by dual-energy X-ray absorptiometry (DEXA-BMD) in males without chronic obstructive pulmonary disease (COPD). In this cross-sectional study, 1,011 males without airflow obstruction >= 50 years old were included. CTBD and DEXA-BMD were compared among groups with different smoking statuses. The correlation between CTBD and DEXA-BMD and the association of CTBD with pack-years were also investigated. CTBD of all vertebral bodies (VBs) and DEXA-BMD of all VBs without L1 showed significant differences among never, former, and current smokers. CTBD was significantly lowest in >= 30-pack-year smokers and was significantly lower in >= 30-pack-year smokers than in <15-pack-year smokers (all P < 0.05). There were significant correlations between DEXA-BMD and CTBD at all VB levels (correlation coefficient [r], 0.448 similar to 0.640; all P < 0.01). A lower CTBD had a significant association with a 15 <= x < 30-pack-year smoking history and >= 30-pack-year smoking history, while there was no association with never-smokers. In conclusion, CTBD demonstrated significant differences in bone quality according to smoking status and pack-years in males without COPD.
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Collections - College of Medicine > Department of Medical Science > 1. Journal Articles
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