Quantitative Analysis on Cellular Uptake of Clustered Ferrite Magnetic Nanoparticles
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Kim, Yu Jin | - |
dc.contributor.author | Park, Bum Chul | - |
dc.contributor.author | Choi, Young Soo | - |
dc.contributor.author | Ko, Min Jun | - |
dc.contributor.author | Kim, Young Keun | - |
dc.date.accessioned | 2021-09-01T12:29:03Z | - |
dc.date.available | 2021-09-01T12:29:03Z | - |
dc.date.created | 2021-06-19 | - |
dc.date.issued | 2019-07 | - |
dc.identifier.issn | 1738-8090 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/64204 | - |
dc.description.abstract | Due to their ability to be internalized into cells by endocytosis through cell membranes, the application of nanoparticles in therapeutic and diagnostic fields has received much interest. In particular, ferrite magnetic nanoparticles (MNPs) are widely used as reagents for medical care, including in vitro magnetic separation, T2-weighted magnetic resonance imaging, magnetic hyperthermia therapy, and as drug delivery systems. However, little is known about the quantitative analysis of the cellular uptake of MNPs by the interaction of particle surfaces with biomolecules. Here, we quantitatively analyze the intracellular uptakes of 30nm Fe- and Mn-ferrite MNPs. We confirm that the magnetic properties of MNPs change according to their microstructure and quantitatively analyze nanoparticle internalization in breast cell lines (MCF10A, MCF7, and MDA-MB-231) by measuring the magnetic moment using a vibrating sample magnetometer. Finally, we examine the effect of nanoparticle microstructure on cellular uptake in terms of the interaction between the nanoparticles and biomolecules. [GRAPHICS] . | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | KOREAN INST METALS MATERIALS | - |
dc.subject | PROTEIN CORONA | - |
dc.subject | GOLD NANOPARTICLES | - |
dc.subject | SURFACE-ROUGHNESS | - |
dc.subject | SIZE | - |
dc.subject | BIOCOMPATIBILITY | - |
dc.subject | NANOMATERIALS | - |
dc.subject | FLUORESCENT | - |
dc.subject | PARTICLES | - |
dc.subject | TOXICITY | - |
dc.title | Quantitative Analysis on Cellular Uptake of Clustered Ferrite Magnetic Nanoparticles | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Kim, Yu Jin | - |
dc.contributor.affiliatedAuthor | Park, Bum Chul | - |
dc.contributor.affiliatedAuthor | Kim, Young Keun | - |
dc.identifier.doi | 10.1007/s13391-019-00141-y | - |
dc.identifier.scopusid | 2-s2.0-85066083297 | - |
dc.identifier.wosid | 000468474000012 | - |
dc.identifier.bibliographicCitation | ELECTRONIC MATERIALS LETTERS, v.15, no.4, pp.471 - 480 | - |
dc.relation.isPartOf | ELECTRONIC MATERIALS LETTERS | - |
dc.citation.title | ELECTRONIC MATERIALS LETTERS | - |
dc.citation.volume | 15 | - |
dc.citation.number | 4 | - |
dc.citation.startPage | 471 | - |
dc.citation.endPage | 480 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.identifier.kciid | ART002465917 | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.description.journalRegisteredClass | kci | - |
dc.relation.journalResearchArea | Materials Science | - |
dc.relation.journalWebOfScienceCategory | Materials Science, Multidisciplinary | - |
dc.subject.keywordPlus | PROTEIN CORONA | - |
dc.subject.keywordPlus | GOLD NANOPARTICLES | - |
dc.subject.keywordPlus | SURFACE-ROUGHNESS | - |
dc.subject.keywordPlus | SIZE | - |
dc.subject.keywordPlus | BIOCOMPATIBILITY | - |
dc.subject.keywordPlus | NANOMATERIALS | - |
dc.subject.keywordPlus | FLUORESCENT | - |
dc.subject.keywordPlus | PARTICLES | - |
dc.subject.keywordPlus | TOXICITY | - |
dc.subject.keywordAuthor | Magnetic nanoparticle | - |
dc.subject.keywordAuthor | Ferrite | - |
dc.subject.keywordAuthor | Biomolecule | - |
dc.subject.keywordAuthor | Cellular uptake | - |
dc.subject.keywordAuthor | Quantitative analysis | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
(02841) 서울특별시 성북구 안암로 14502-3290-1114
COPYRIGHT © 2021 Korea University. All Rights Reserved.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.