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Pyranoflavanones and Pyranochalcones from the Fruits of Amomum tsao-ko

Authors
Kim, Jun GuJang, HariThi Phuong Linh LeHong, Hye RyoungLee, Mi KyeongHong, Jin TaeLee, DonghoHwang, Bang Yeon
Issue Date
7월-2019
Publisher
AMER CHEMICAL SOC
Citation
JOURNAL OF NATURAL PRODUCTS, v.82, no.7, pp.1886 - 1892
Indexed
SCIE
SCOPUS
Journal Title
JOURNAL OF NATURAL PRODUCTS
Volume
82
Number
7
Start Page
1886
End Page
1892
URI
https://scholar.korea.ac.kr/handle/2021.sw.korea/64681
DOI
10.1021/acs.jnatprod.9b00155
ISSN
0163-3864
Abstract
Eight new geranylated and farnesylated pyranoflavanones (1-8) and two new famesylated pyranochalcones (9 and 10) were isolated from the methanolic extract of the fruits of Amomum tsao-ko. Their structures were elucidated by extensive analysis of the 1D and 2D NMR spectra and from the HRESIMS, combined with experimental ECD data. All compounds were evaluated for their inhibitory effects on the nitric oxide production against lipopolysaccharide-induced RAW 264.7 macrophages and exhibited IC50 values ranging from 10.6 to 41.5 mu M.
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