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High Stability of a Donor-Acceptor Type Oxazepine-Containing Fluorophore and Its Applications in Cellular Imaging and Two-Photon Deep Tissue Imaging

Authors
Moon, HeejoJung, YunaKim, YoungseoKim, Byeonz WookChoi, Jin GyuKim, Na HeeOh, Myung SookPark, SungnamKim, B. MoonKim, Dokyoung
Issue Date
7-6월-2019
Publisher
AMER CHEMICAL SOC
Citation
ORGANIC LETTERS, v.21, no.11, pp.3891 - 3894
Indexed
SCIE
SCOPUS
Journal Title
ORGANIC LETTERS
Volume
21
Number
11
Start Page
3891
End Page
3894
URI
https://scholar.korea.ac.kr/handle/2021.sw.korea/64788
DOI
10.1021/acs.orglett.9b00784
ISSN
1523-7060
Abstract
A new donor (D)-acceptor (A) type naphthalene-based oxazepine-containing fluorophore, OXN-1, is reported, which shows unusually high stability in various environments. Its photophysical properties and structural stabilities under harsh conditions are thoroughly examined. The high stability of OXN-1 is explained by quantum chemical calculations. Its exceptional bioimaging capabilities for cells with low cytotoxicity are verified. In addition, its deep tissue imaging ability with two-photon microscopy (TPM) is evaluated.
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