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A coumarin-naphthalimide hybrid as a dual emissive fluorescent probe for hNQO1
- Issue Date
- May-2019
- Publisher
- ELSEVIER SCI LTD
- Keywords
- hNQO1 detection; Dual emission imaging; Naphthalimide; Coumarin
- Citation
- DYES AND PIGMENTS, v.164, pp.341 - 345
- Indexed
- SCIE
SCOPUS
- Journal Title
- DYES AND PIGMENTS
- Volume
- 164
- Start Page
- 341
- End Page
- 345
- ISSN
- 0143-7208
- Abstract
- hNQO1 is a promising target for cancer diagnosis and treatment. Here, we developed a coumarin-naphthalimide hybrid (1) as a dual emissive fluorescent probe that enhances the emission through hNQO1-mediated cleavage of its trimethyl lockquinone moiety. Probe 1 can be used for a real-time monitoring of hNQO1 activity in living cells.
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Collections - College of Science > Department of Chemistry > 1. Journal Articles
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Related Researcher
- Kim, Jong Seung
- College of Science (Department of Chemistry)