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Artificial Neural Network Analysis of Spontaneous Preterm Labor and Birth and Its Major Determinants

Authors
Lee, Kwang-SigAhn, Ki Hoon
Issue Date
29-4월-2019
Publisher
KOREAN ACAD MEDICAL SCIENCES
Keywords
Preterm Birth; Hypertension; Diabetes Mellitus; Prior Conization; Cervical-Length Screening
Citation
JOURNAL OF KOREAN MEDICAL SCIENCE, v.34, no.16
Indexed
SCIE
SCOPUS
KCI
Journal Title
JOURNAL OF KOREAN MEDICAL SCIENCE
Volume
34
Number
16
URI
https://scholar.korea.ac.kr/handle/2021.sw.korea/65958
DOI
10.3346/jkms.2019.34.e128
ISSN
1011-8934
Abstract
Background: Little research based on the artificial neural network (ANN) is done on preterm birth (spontaneous preterm labor and birth) and its major determinants. This study uses an ANN for analyzing preterm birth and its major determinants. Methods: Data came from Anam Hospital in Seoul, Korea, with 596 obstetric patients during March 27, 2014 - August 21, 2018. Six machine learning methods were applied and compared for the prediction of preterm birth. Variable importance, the effect of a variable on model performance, was used for identifying major determinants of preterm birth. Analysis was done in December, 2018. Results: The accuracy of the ANN (0.9115) was similar with those of logistic regression and the random forest (0.9180 and 0.8918, respectively). Based on variable importance from the ANN, major determinants of preterm birth are body mass index (0.0164), hypertension (0.0131) and diabetes mellitus (0.0099) as well as prior cone biopsy (0.0099), prior placenta previa (0.0099), parity (0.0033), cervical length (0.0001), age (0.0001), prior preterm birth (0.0001) and myomas & adenomyosis (0.0001). Conclusion: For preventing preterm birth, preventive measures for hypertension and diabetes mellitus are required alongside the promotion of cervical-length screening with different guidelines across the scope/type of prior conization.
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