The Role of the Medial Habenula Cholinergic System in Addiction and Emotion-Associated Behaviors
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Lee, Hyun Woo | - |
dc.contributor.author | Yang, Soo Hyun | - |
dc.contributor.author | Kim, Jin Yong | - |
dc.contributor.author | Kim, Hyun | - |
dc.date.accessioned | 2021-09-01T18:25:37Z | - |
dc.date.available | 2021-09-01T18:25:37Z | - |
dc.date.created | 2021-06-19 | - |
dc.date.issued | 2019-02-28 | - |
dc.identifier.issn | 1664-0640 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/67269 | - |
dc.description.abstract | The habenula is a complex nucleus composed of lateral and medial subnuclei, which connect between the limbic forebrain and midbrain. Over the past few years, the lateral habenula has received considerable attention because of its potential roles in cognition and in the pathogenesis of various psychiatric disorders. Unlike extensively studied lateral habenula, anatomically and histologically distinct medial habenula remains largely understudied. The medial habenula can be further subdivided into a dorsal region containing excitatory neurons that express the tachykinin neuropeptide substance P and a ventral region containing dense cholinergic neurons. Although the medial habenula is the source of one of the major cholinergic pathways in the brain, relatively few studies have been conducted to understand its roles. Recently, however, the medial habenula cholinergic system has attracted more attention because of its potential to provide therapeutic targets for the treatment of nicotine withdrawal symptoms, drug addiction, and various mood disorders. Here, we discuss the role of the medial habenula cholinergic system in brain function. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | FRONTIERS MEDIA SA | - |
dc.subject | NICOTINIC ACETYLCHOLINE-RECEPTORS | - |
dc.subject | INTERPEDUNCULAR NUCLEUS | - |
dc.subject | GABAERGIC NEURONS | - |
dc.subject | PREFRONTAL CORTEX | - |
dc.subject | LUNG-CANCER | - |
dc.subject | RAT | - |
dc.subject | CONNECTIONS | - |
dc.subject | WITHDRAWAL | - |
dc.subject | DEPENDENCE | - |
dc.subject | MORPHINE | - |
dc.title | The Role of the Medial Habenula Cholinergic System in Addiction and Emotion-Associated Behaviors | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Lee, Hyun Woo | - |
dc.contributor.affiliatedAuthor | Kim, Hyun | - |
dc.identifier.doi | 10.3389/fpsyt.2019.00100 | - |
dc.identifier.scopusid | 2-s2.0-85065982564 | - |
dc.identifier.wosid | 000459865200001 | - |
dc.identifier.bibliographicCitation | FRONTIERS IN PSYCHIATRY, v.10 | - |
dc.relation.isPartOf | FRONTIERS IN PSYCHIATRY | - |
dc.citation.title | FRONTIERS IN PSYCHIATRY | - |
dc.citation.volume | 10 | - |
dc.type.rims | ART | - |
dc.type.docType | Review | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | ssci | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Psychiatry | - |
dc.relation.journalWebOfScienceCategory | Psychiatry | - |
dc.subject.keywordPlus | NICOTINIC ACETYLCHOLINE-RECEPTORS | - |
dc.subject.keywordPlus | INTERPEDUNCULAR NUCLEUS | - |
dc.subject.keywordPlus | GABAERGIC NEURONS | - |
dc.subject.keywordPlus | PREFRONTAL CORTEX | - |
dc.subject.keywordPlus | LUNG-CANCER | - |
dc.subject.keywordPlus | RAT | - |
dc.subject.keywordPlus | CONNECTIONS | - |
dc.subject.keywordPlus | WITHDRAWAL | - |
dc.subject.keywordPlus | DEPENDENCE | - |
dc.subject.keywordPlus | MORPHINE | - |
dc.subject.keywordAuthor | habenula | - |
dc.subject.keywordAuthor | cholinergic system | - |
dc.subject.keywordAuthor | nicotine addiction and withdrawal | - |
dc.subject.keywordAuthor | drug addiction | - |
dc.subject.keywordAuthor | fear | - |
dc.subject.keywordAuthor | depression | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
(02841) 서울특별시 성북구 안암로 14502-3290-1114
COPYRIGHT © 2021 Korea University. All Rights Reserved.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.