Detailed Information

Cited 0 time in webofscience Cited 0 time in scopus
Metadata Downloads

The Role of the Medial Habenula Cholinergic System in Addiction and Emotion-Associated Behaviors

Authors
Lee, Hyun WooYang, Soo HyunKim, Jin YongKim, Hyun
Issue Date
28-2월-2019
Publisher
FRONTIERS MEDIA SA
Keywords
habenula; cholinergic system; nicotine addiction and withdrawal; drug addiction; fear; depression
Citation
FRONTIERS IN PSYCHIATRY, v.10
Indexed
SCIE
SSCI
SCOPUS
Journal Title
FRONTIERS IN PSYCHIATRY
Volume
10
URI
https://scholar.korea.ac.kr/handle/2021.sw.korea/67269
DOI
10.3389/fpsyt.2019.00100
ISSN
1664-0640
Abstract
The habenula is a complex nucleus composed of lateral and medial subnuclei, which connect between the limbic forebrain and midbrain. Over the past few years, the lateral habenula has received considerable attention because of its potential roles in cognition and in the pathogenesis of various psychiatric disorders. Unlike extensively studied lateral habenula, anatomically and histologically distinct medial habenula remains largely understudied. The medial habenula can be further subdivided into a dorsal region containing excitatory neurons that express the tachykinin neuropeptide substance P and a ventral region containing dense cholinergic neurons. Although the medial habenula is the source of one of the major cholinergic pathways in the brain, relatively few studies have been conducted to understand its roles. Recently, however, the medial habenula cholinergic system has attracted more attention because of its potential to provide therapeutic targets for the treatment of nicotine withdrawal symptoms, drug addiction, and various mood disorders. Here, we discuss the role of the medial habenula cholinergic system in brain function.
Files in This Item
There are no files associated with this item.
Appears in
Collections
Graduate School > Department of Biomedical Sciences > 1. Journal Articles

qrcode

Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.

Related Researcher

Researcher Kim, Hyun photo

Kim, Hyun
의과학과
Read more

Altmetrics

Total Views & Downloads

BROWSE