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Dual-functional fluorescent molecular rotor for endoplasmic reticulum microviscosity imaging during reticulophagy

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dc.contributor.authorHe, Ying-
dc.contributor.authorShin, Jinwoo-
dc.contributor.authorGong, Wanjun-
dc.contributor.authorDas, Pintu-
dc.contributor.authorQu, Jinghan-
dc.contributor.authorYang, Zhigang-
dc.contributor.authorLiu, Wufan-
dc.contributor.authorKang, Chulhun-
dc.contributor.authorQu, Junle-
dc.contributor.authorKim, Jong Seung-
dc.date.accessioned2021-09-01T18:26:06Z-
dc.date.available2021-09-01T18:26:06Z-
dc.date.created2021-06-18-
dc.date.issued2019-02-28-
dc.identifier.issn1359-7345-
dc.identifier.urihttps://scholar.korea.ac.kr/handle/2021.sw.korea/67273-
dc.description.abstractThe microviscosity change associated with reticulophagy is an important component for studying endoplasmic reticulum (ER) stress disorders. Here, a BODIPY-arsenicate conjugate 1-based fluorescent molecular rotor was designed to covalently bind vicinal dithiol-containing proteins in the ER, exhibiting a bifunction of reticulophagy initiation and microviscosity evaluation. Therefore, we could quantify the local viscosity changes during reticulophagy based on the fluorescence lifetime changes of probe 1.-
dc.languageEnglish-
dc.language.isoen-
dc.publisherROYAL SOC CHEMISTRY-
dc.subjectDITHIOL-CONTAINING PROTEINS-
dc.subjectER STRESS-
dc.subjectARSENIC-BINDING-
dc.subjectVISCOSITY-
dc.subjectAUTOPHAGY-
dc.subjectPROBE-
dc.subjectLC3B-
dc.subjectCELL-
dc.subjectMITOCHONDRIA-
dc.subjectTARGET-
dc.titleDual-functional fluorescent molecular rotor for endoplasmic reticulum microviscosity imaging during reticulophagy-
dc.typeArticle-
dc.contributor.affiliatedAuthorKim, Jong Seung-
dc.identifier.doi10.1039/c9cc00300b-
dc.identifier.scopusid2-s2.0-85061973737-
dc.identifier.wosid000459474300007-
dc.identifier.bibliographicCitationCHEMICAL COMMUNICATIONS, v.55, no.17, pp.2453 - 2456-
dc.relation.isPartOfCHEMICAL COMMUNICATIONS-
dc.citation.titleCHEMICAL COMMUNICATIONS-
dc.citation.volume55-
dc.citation.number17-
dc.citation.startPage2453-
dc.citation.endPage2456-
dc.type.rimsART-
dc.type.docTypeArticle-
dc.description.journalClass1-
dc.description.journalRegisteredClassscie-
dc.description.journalRegisteredClassscopus-
dc.relation.journalResearchAreaChemistry-
dc.relation.journalWebOfScienceCategoryChemistry, Multidisciplinary-
dc.subject.keywordPlusDITHIOL-CONTAINING PROTEINS-
dc.subject.keywordPlusER STRESS-
dc.subject.keywordPlusARSENIC-BINDING-
dc.subject.keywordPlusVISCOSITY-
dc.subject.keywordPlusAUTOPHAGY-
dc.subject.keywordPlusPROBE-
dc.subject.keywordPlusLC3B-
dc.subject.keywordPlusCELL-
dc.subject.keywordPlusMITOCHONDRIA-
dc.subject.keywordPlusTARGET-
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