Extremely sensitive and wide-range silver ion detection via assessing the integrated surface potential of a DNA-capped gold nanoparticle
- Authors
- Lee, Dongtak; Lee, Hyungbeen; Lee, Gyudo; Kim, Insu; Lee, Sang Won; Kim, Woong; Lee, Sang Woo; Lee, Jeong Hoon; Park, Jinsung; Yoon, Dae Sung
- Issue Date
- 22-2월-2019
- Publisher
- IOP PUBLISHING LTD
- Keywords
- silver ion; DNA-metal interaction; Kevin probe force microscope; gold nanoparticle; surface potential
- Citation
- NANOTECHNOLOGY, v.30, no.8
- Indexed
- SCIE
SCOPUS
- Journal Title
- NANOTECHNOLOGY
- Volume
- 30
- Number
- 8
- URI
- https://scholar.korea.ac.kr/handle/2021.sw.korea/67291
- DOI
- 10.1088/1361-6528/aaf66f
- ISSN
- 0957-4484
- Abstract
- With the rapid development of nanotechnology and its associated waste stream, public concern is growing over the potential toxicity exposure to heavy metal ions poses to the human body and the environment. Herein, we report an extremely sensitive Kelvin probe force microscopy (KPFM)-based platform for detecting nanotoxic materials (e.g. Ag+) accomplished by probing the integrated surface potential differences of a single gold nanoparticle on which an interaction between probe DNA and target DNA occurs. This interaction can amplify the surface potential of the nanoparticle owing to the coordination bond mediated by Ag+ (cytosine-Ag+-cytosine base pairs). Interestingly, compared with conventional methods, this platform is capable of extremely sensitive Ag(+ )detection (similar to 1 fM) in a remarkably wide-range (1 fM to 1 mu M). Furthermore, this platform enables Ag+ detection in a practical sample (general drinking water), and this KPFM-based technique may have the potential to detect other toxic heavy metal ions and single nucleotide polymorphisms by designing specific DNA sequences.
- Files in This Item
- There are no files associated with this item.
- Appears in
Collections - Graduate School > Department of Biotechnology and Bioinformatics > 1. Journal Articles
- Graduate School > Department of Control and Instrumentation Engineering > 1. Journal Articles
- Graduate School > Department of Bioengineering > 1. Journal Articles
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.