Reflection phase microscopy using spatio-temporal coherence of light
DC Field | Value | Language |
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dc.contributor.author | Choi, Youngwoon | - |
dc.contributor.author | Hosseini, Poorya | - |
dc.contributor.author | Kang, Jeon Woong | - |
dc.contributor.author | Kang, Sungsam | - |
dc.contributor.author | Yang, Taeseok Daniel | - |
dc.contributor.author | Hyeon, Min Gyu | - |
dc.contributor.author | Kim, Beop-Min | - |
dc.contributor.author | So, Peter T. C. | - |
dc.contributor.author | Yaqoob, Zahid | - |
dc.date.accessioned | 2021-09-02T03:19:44Z | - |
dc.date.available | 2021-09-02T03:19:44Z | - |
dc.date.created | 2021-06-19 | - |
dc.date.issued | 2018-11-20 | - |
dc.identifier.issn | 2334-2536 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/71822 | - |
dc.description.abstract | Many disease states are associated with cellular biomechanical changes as markers. Label-free phase microscopes are used to quantify thermally driven interface fluctuations, which allow the deduction of important cellular rheological properties. Here, the spatio-temporal coherence of light was used to implement a high-speed reflection phase micro- scope with superior depth selectivity and higher phase sensitivity. Nanometric scale motion of cytoplasmic structures can be visualized with fine details and three-dimensional resolution. Specifically, the spontaneous fluctuation occurring on the nuclear membrane of a living cell was observed at video rate. By converting the reflection phase into displacement, the sensitivity in quantifying nuclear membrane fluctuation was found to be about one nanometer. A reflection phase microscope can potentially elucidate biomechanical mechanisms of pathological and physiological processes. (C) 2018 Optical Society of America under the terms of the OSA Open Access Publishing Agreement | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | OPTICAL SOC AMER | - |
dc.subject | DIGITAL HOLOGRAPHIC MICROSCOPY | - |
dc.subject | SUPERCONTINUUM GENERATION | - |
dc.subject | SPECKLE ILLUMINATION | - |
dc.subject | PHOTONIC CRYSTAL | - |
dc.subject | TOMOGRAPHY | - |
dc.subject | DYNAMICS | - |
dc.subject | CELLS | - |
dc.subject | INTERFEROMETRY | - |
dc.subject | DISEASE | - |
dc.subject | FIBERS | - |
dc.title | Reflection phase microscopy using spatio-temporal coherence of light | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Choi, Youngwoon | - |
dc.contributor.affiliatedAuthor | Yang, Taeseok Daniel | - |
dc.contributor.affiliatedAuthor | Kim, Beop-Min | - |
dc.identifier.doi | 10.1364/OPTICA.5.001468 | - |
dc.identifier.scopusid | 2-s2.0-85059028205 | - |
dc.identifier.wosid | 000450664900017 | - |
dc.identifier.bibliographicCitation | OPTICA, v.5, no.11, pp.1468 - 1473 | - |
dc.relation.isPartOf | OPTICA | - |
dc.citation.title | OPTICA | - |
dc.citation.volume | 5 | - |
dc.citation.number | 11 | - |
dc.citation.startPage | 1468 | - |
dc.citation.endPage | 1473 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Optics | - |
dc.relation.journalWebOfScienceCategory | Optics | - |
dc.subject.keywordPlus | DIGITAL HOLOGRAPHIC MICROSCOPY | - |
dc.subject.keywordPlus | SUPERCONTINUUM GENERATION | - |
dc.subject.keywordPlus | SPECKLE ILLUMINATION | - |
dc.subject.keywordPlus | PHOTONIC CRYSTAL | - |
dc.subject.keywordPlus | TOMOGRAPHY | - |
dc.subject.keywordPlus | DYNAMICS | - |
dc.subject.keywordPlus | CELLS | - |
dc.subject.keywordPlus | INTERFEROMETRY | - |
dc.subject.keywordPlus | DISEASE | - |
dc.subject.keywordPlus | FIBERS | - |
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