A new risk score for ventricular tachyarrhythmia in acute myocardial infarction with preserved left ventricular ejection fraction
- Authors
- Lee, Seung Hun; Jeong, Myung Ho; Kim, Ju Han; Kim, Min Chul; Sim, Doo Sun; Hong, Young Joon; Ahn, Youngkeun; Chae, Shung Chull; Seong, In Whan; Park, Jong Sun; Chae, Jei Keon; Hur, Seung Ho; Cha, Kwang-Soo; Kim, Hyo-Soo; Gwon, Hyeon Cheol; Seung, Ki Bae; Rha, Seung Woon
- Issue Date
- Nov-2018
- Publisher
- ELSEVIER SCIENCE BV
- Keywords
- Ventricular tachycardia; Ventricular fibrillation; Myocardial infarction; Prognosis
- Citation
- JOURNAL OF CARDIOLOGY, v.72, no.5-6, pp.420 - 426
- Indexed
- SCIE
SCOPUS
- Journal Title
- JOURNAL OF CARDIOLOGY
- Volume
- 72
- Number
- 5-6
- Start Page
- 420
- End Page
- 426
- URI
- https://scholar.korea.ac.kr/handle/2021.sw.korea/71923
- DOI
- 10.1016/j.jjcc.2018.04.008
- ISSN
- 0914-5087
- Abstract
- Background: Ventricular tachycardia or fibrillation (VT/VF) is a major cause of sudden cardiac death after acute myocardial infarction (AMI). This study aims to investigate the clinical characteristics and outcomes of VT/VF, to identify the variables associated with VT/VF, and to construct a new scoring system. Methods: Patients with relatively preserved left ventricular ejection fraction (LVEF) (>40%) included in the Korea Acute Myocardial Infarction Registry-National Institutes of Health registry were enrolled in this study. Among 13,109 patients in the registry, a total of 10,334 (78.8%) had relatively preserved LVEF after AMI. Patients were divided into two groups based on whether they experienced life-threatening VT/VF during hospitalization or not. The predictors for VT/VF during hospitalization were assessed. In-hospital mortality and complications were recorded. Results: A total of 358 (3.5%) experienced life-threatening VT/VF. The VT/VF group was at an increased risk of in-hospital mortality (odds ratio 2.99) and cardiac death (odds ratio 3.40). Variables of diagnosis, Killip class, smoking, initial rhythm, left bundle branch block, and LVEF were significant indicators of VT/ VF. A new risk score system yielded acceptable discrimination function (c-statistics = 0.773). Conclusions: Relatively preserved LVEF patients could still be at risk of life-threatening VT/VF, which is related to a poor prognosis during the admission period. This new scoring system can be adopted to stratify the risk of VT/VF. (C) 2018 Japanese College of Cardiology. Published by Elsevier Ltd. All rights reserved.
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Collections - Graduate School > Department of Biomedical Sciences > 1. Journal Articles
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