Comparison of radiation therapy modalities for hepatocellular carcinoma with portal vein thrombosis: A meta-analysis and systematic review
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Rim, Chai Hong | - |
dc.contributor.author | Kim, Chul Yong | - |
dc.contributor.author | Yang, Dae Sik | - |
dc.contributor.author | Yoon, Won Sup | - |
dc.date.accessioned | 2021-09-02T05:23:30Z | - |
dc.date.available | 2021-09-02T05:23:30Z | - |
dc.date.created | 2021-06-19 | - |
dc.date.issued | 2018-10 | - |
dc.identifier.issn | 0167-8140 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/72571 | - |
dc.description.abstract | Purpose: We performed a meta-analysis and systematic review to compare the radiotherapy (RT) modalities for hepatocellular carcinoma (HCC) with portal vein thrombosis (PVT). Materials and methods: We searched the PubMed, EMBASE, Medline, and Cochrane library databases. The primary endpoint was the 1-year overall survival (OS), and response rate (RR), local control (LC), 2-year OS, and grade >= 3 toxicity incidence were evaluated as secondary endpoints. Results: Thirty-seven studies comprising 2513 patients were included. The pooled 1-year OS rates for the 3-dimensional conformal RT (3DCRT), selective internal RT (SIRT), and stereotactic body RT (SBRT) groups were 43.8% [ 95% confidence interval (CI): 37.6-50.2], 46.5% (95% CI: 37.7-55.6), and 48.5% (95% CI: 39.457.8). These inter-group differences were not statistically significant (p = 0.635). The pooled response rates were 51.3% (95% CI: 45.7-57.0), 33.3% (95% CI: 18.0-53.2), and 70.7 (95% CI: 63.7-76.8) for 3DCRT, SIRT, and SBRT groups, respectively; p = 0.001 and 0.031 for 3DCRT vs. SBRT and SIRT, respectively. The most common grade >= 3 complications were lymphocytopenia and bilirubin abnormalities in the 3DCRT and SIRT groups, respectively. Grade >= 3 complication was rare in SBRT group. Conclusions: OS did not differ among the modalities, although the response rates vary among modalities. (C) 2017 Elsevier B. V. All rights reserved. Radiotherapy and Oncology | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | ELSEVIER IRELAND LTD | - |
dc.subject | TRANSCATHETER ARTERIAL CHEMOEMBOLIZATION | - |
dc.subject | 3-DIMENSIONAL CONFORMAL RADIOTHERAPY | - |
dc.subject | STEREOTACTIC BODY RADIOTHERAPY | - |
dc.subject | PRIMARY LIVER-CANCER | - |
dc.subject | TUMOR THROMBOSIS | - |
dc.subject | TRANSARTERIAL CHEMOEMBOLIZATION | - |
dc.subject | INFUSION CHEMOTHERAPY | - |
dc.subject | GLASS MICROSPHERES | - |
dc.subject | Y-90 MICROSPHERES | - |
dc.subject | RADIOEMBOLIZATION | - |
dc.title | Comparison of radiation therapy modalities for hepatocellular carcinoma with portal vein thrombosis: A meta-analysis and systematic review | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Rim, Chai Hong | - |
dc.contributor.affiliatedAuthor | Kim, Chul Yong | - |
dc.contributor.affiliatedAuthor | Yang, Dae Sik | - |
dc.contributor.affiliatedAuthor | Yoon, Won Sup | - |
dc.identifier.doi | 10.1016/j.radonc.2017.11.013 | - |
dc.identifier.scopusid | 2-s2.0-85037655356 | - |
dc.identifier.wosid | 000449458600017 | - |
dc.identifier.bibliographicCitation | RADIOTHERAPY AND ONCOLOGY, v.129, no.1, pp.112 - 122 | - |
dc.relation.isPartOf | RADIOTHERAPY AND ONCOLOGY | - |
dc.citation.title | RADIOTHERAPY AND ONCOLOGY | - |
dc.citation.volume | 129 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 112 | - |
dc.citation.endPage | 122 | - |
dc.type.rims | ART | - |
dc.type.docType | Review | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Oncology | - |
dc.relation.journalResearchArea | Radiology, Nuclear Medicine & Medical Imaging | - |
dc.relation.journalWebOfScienceCategory | Oncology | - |
dc.relation.journalWebOfScienceCategory | Radiology, Nuclear Medicine & Medical Imaging | - |
dc.subject.keywordPlus | TRANSCATHETER ARTERIAL CHEMOEMBOLIZATION | - |
dc.subject.keywordPlus | 3-DIMENSIONAL CONFORMAL RADIOTHERAPY | - |
dc.subject.keywordPlus | STEREOTACTIC BODY RADIOTHERAPY | - |
dc.subject.keywordPlus | PRIMARY LIVER-CANCER | - |
dc.subject.keywordPlus | TUMOR THROMBOSIS | - |
dc.subject.keywordPlus | TRANSARTERIAL CHEMOEMBOLIZATION | - |
dc.subject.keywordPlus | INFUSION CHEMOTHERAPY | - |
dc.subject.keywordPlus | GLASS MICROSPHERES | - |
dc.subject.keywordPlus | Y-90 MICROSPHERES | - |
dc.subject.keywordPlus | RADIOEMBOLIZATION | - |
dc.subject.keywordAuthor | Radiotherapy | - |
dc.subject.keywordAuthor | Hepatocellular carcinoma | - |
dc.subject.keywordAuthor | Portal vein thrombosis | - |
dc.subject.keywordAuthor | Selective internal radiotherapy | - |
dc.subject.keywordAuthor | Stereotactic body radiotherapy | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
(02841) 서울특별시 성북구 안암로 14502-3290-1114
COPYRIGHT © 2021 Korea University. All Rights Reserved.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.