Fluorescent Molecular Rotors for Viscosity Sensors
- Authors
- Lee, Seung-Chul; Heo, Jeongyun; Woo, Hee Chul; Lee, Ji-Ah; Seo, Young Hun; Lee, Chang-Lyoul; Kim, Sehoon; Kwon, O-Pil
- Issue Date
- 18-9월-2018
- Publisher
- WILEY-V C H VERLAG GMBH
- Keywords
- fluorescence dynamics; fluorescent molecular rotors; microviscosity; molecular rotors; viscosity sensors
- Citation
- CHEMISTRY-A EUROPEAN JOURNAL, v.24, no.52, pp.13706 - 13718
- Indexed
- SCIE
SCOPUS
- Journal Title
- CHEMISTRY-A EUROPEAN JOURNAL
- Volume
- 24
- Number
- 52
- Start Page
- 13706
- End Page
- 13718
- URI
- https://scholar.korea.ac.kr/handle/2021.sw.korea/73083
- DOI
- 10.1002/chem.201801389
- ISSN
- 0947-6539
- Abstract
- Fluorescent molecular rotors (FMRs) can act as viscosity sensors in various media including subcellular organelles and microfluidic channels. In FMRs, the rotation of rotators connected to a fluorescent pi-conjugated bridge is suppressed by increasing environmental viscosity, resulting in increasing fluorescence (FL) intensity. In this minireview, we describe recently developed FMRs including push-pull type pi-conjugated chromophores, meso-phenyl (borondipyrromethene) (BODIPY) derivatives, dioxaborine derivatives, cyanine derivatives, and porphyrin derivatives whose FL mechanism is viscosity-responsive. In addition, FMR design strategies for addressing various issues (e.g., obtaining high FL contrast, internal FL references, and FL intensity-contrast trade-off) and their biological and microfluidic applications are also discussed.
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Collections - Graduate School > KU-KIST Graduate School of Converging Science and Technology > 1. Journal Articles
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