Chronic total occlusion intervention of the non-infarct-related artery in acute myocardial infarction patients: the Korean multicenter chronic total occlusion registry
- Authors
- Park, Ji Young; Choi, Byoung Geol; Rha, Seung-Woon; Kang, Tae Soo; Choi, Cheol Ung; Yu, Cheol Woong; Gwon, Hyeon-Cheol; Chae, In-Ho; Kim, Hyo-Soo; Park, Hun Sik; Lee, Seung-Hwan; Kim, Moo-Hyun; Hur, Seung-Ho; Jang, Yangsoo
- Issue Date
- Sep-2018
- Publisher
- LIPPINCOTT WILLIAMS & WILKINS
- Keywords
- acute myocardial infarction; chronic total occlusion; percutaneous coronary intervention
- Citation
- CORONARY ARTERY DISEASE, v.29, no.6, pp 495 - 501
- Pages
- 7
- Indexed
- SCI
SCIE
SCOPUS
- Journal Title
- CORONARY ARTERY DISEASE
- Volume
- 29
- Number
- 6
- Start Page
- 495
- End Page
- 501
- URI
- https://scholar.korea.ac.kr/handle/2021.sw.korea/73246
- DOI
- 10.1097/MCA.0000000000000630
- ISSN
- 0954-6928
1473-5830
- Abstract
- BackgroundThe Korean chronic total occlusion (CTO) registry was collected prospectively from 26 cardiovascular centers since May 2007. The aim of this study is to investigate the impact of a successful staged percutaneous coronary intervention (PCI) of CTO lesions in acute myocardial infarction (AMI) patients on clinical outcomes.Patients and methodsAmong 2813 patients who underwent a staged PCI because of CTO lesions, 422 (15%) patients underwent primary PCI because of AMI. Among 422 patients, successful staged CTO-PCI was performed in 76%. The clinical outcomes were compared between the successful CTO-PCI group (n=321) and the failed CTO-PCI group (n=101). To adjust for potential confounders, a propensity score matching (PSM) analysis was carried out using the logistic regression model.ResultsAfter the PSM analysis, two propensity-matched groups (85 pairs, n=170) were generated and the baseline characteristics were balanced. The incidence of total death (P=0.029) and non-ST-segment elevation myocardial infarction (NSTEMI, P=0.043) at 1 year was higher in the failed CTO-PCI group. Multivariate regression showed that successful CTO-PCI was an independent predictor of preventing mortality (hazard ratio, 0.21, P=0.048). In the subgroup analysis, the Kaplan-Meier curve showed that successful CTO-PCI had a lower incidence of total death (log-rank=0.004) and cardiac death (log-rank=0.005) up to 1 year in NSTEMI patients. Cox-proportional analysis showed that successful CTO-PCI was beneficial in patients with NSTEMI, hypertension, and non-left-anterior descending artery lesion for preventing mortality.ConclusionIn this study, a staged successful CTO-PCI in AMI patients was associated with improved 1-year survival in the Korean population.
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Collections - Graduate School > Department of Biomedical Sciences > 1. Journal Articles
- College of Medicine > Department of Medical Science > 1. Journal Articles

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