Metal-free approach for the L-proline mediated synthesis of nitrones from nitrosobenzene
- Authors
- Choi, Minho; Viji, Mayavan; Kim, Donghwan; Lee, Young Hee; Sim, Jaeuk; Kwak, Young-Shin; Lee, Kiho; Lee, Heesoon; Jung, Jae-Kyung
- Issue Date
- 2-8월-2018
- Publisher
- PERGAMON-ELSEVIER SCIENCE LTD
- Keywords
- Nitrones; Metal-free; L-proline; Nitrosobenzene; Azomethine ylide
- Citation
- TETRAHEDRON, v.74, no.31, pp.4182 - 4187
- Indexed
- SCIE
SCOPUS
- Journal Title
- TETRAHEDRON
- Volume
- 74
- Number
- 31
- Start Page
- 4182
- End Page
- 4187
- URI
- https://scholar.korea.ac.kr/handle/2021.sw.korea/73798
- DOI
- 10.1016/j.tet.2018.06.001
- ISSN
- 0040-4020
- Abstract
- An efficient, and metal-free approach for the L-proline mediated synthesis of nitrones from nitro-sobenzene and benzaldehydes has been established. The reaction undergoes very efficiently at room temperature in methanol as a solvent. The reaction is assumed to involve that the initial formation of azomethine ylide and [2 + 3] cycloaddition of nitrosobenzene, followed by the subsequent retro [2 + 3] cycloaddition could offer the desired nitrone. (c) 2018 Elsevier Ltd. All rights reserved.
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Collections - College of Pharmacy > Department of Pharmaceutical Science > 1. Journal Articles
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