Ischemic stroke risk during long-term follow up in patients with successful catheter ablation for atrial fibrillation in Korea
DC Field | Value | Language |
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dc.contributor.author | Kim, Dong-Hyeok | - |
dc.contributor.author | Lee, Dae-In | - |
dc.contributor.author | Ahn, Jinhee | - |
dc.contributor.author | Lee, Kwang-No | - |
dc.contributor.author | Roh, Seung-Young | - |
dc.contributor.author | Shim, Jaemin | - |
dc.contributor.author | Choi, Jong-Il | - |
dc.contributor.author | Kim, Young-Hoon | - |
dc.date.accessioned | 2021-09-02T08:54:52Z | - |
dc.date.available | 2021-09-02T08:54:52Z | - |
dc.date.created | 2021-06-16 | - |
dc.date.issued | 2018-07-19 | - |
dc.identifier.issn | 1932-6203 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/74322 | - |
dc.description.abstract | The interruption of oral anticoagulation therapy (OAC) after CA of atrial fibrillation (AF) is controversial. The purpose of this study was to evaluate the relationship between successful long-term outcomes of catheter resection and SR maintenance and ischemic stroke risk in Korea. We studied 1,548 consecutive patients who were followed up for more than 2 years after CA of AF. We investigated the incidence of ischemic stroke during long-term follow-up. Compared to the AF recurrence group (n = 619), the sinus rhythm (SR) maintenance group (n = 929) had more paroxysmal AF (74.6% versus 44.4%, p<0.001), smaller LA size (39.9 +/- 5.7mm versus 42.3 +/- 6.0mm, p<0.001), and younger age (54.2 +/- 10.9 years versus 56.4 +/- 10.6 years, p<0.001). However, CHA(2)DS(2)-VASc scores were not significantly different between the two groups (0.9 vs. 1.1, p = 0.053). The overall incidence of ischemic stroke during the mean follow-up period of 54 months after CA was 0.6%, and was significantly lower in the SR group than the AF recurrence group (0.3% vs. 1.1%, log-rank test p<0.001). However, in sub-analysis in the SR group, the rate of ischemic stroke was significantly increasing in patients with a CHA(2)DS(2)-VASc score >= 4 compared to those with a CHA(2)DS(2)-VASc score < 4 (4.3% vs. 0.2%, log-rank test p<0.001). In conclusion, this long-term followup data in patients with AF who underwent successful CA showed that SR maintenance was correlated with a lower rate of ischemic stroke in Korea. However, it was only observed in patients with CHA(2)DS(2)-VASc score <= 3. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | PUBLIC LIBRARY SCIENCE | - |
dc.subject | RADIOFREQUENCY ABLATION | - |
dc.subject | THROMBOEMBOLIC EVENTS | - |
dc.subject | ORAL ANTICOAGULATION | - |
dc.subject | THERAPY | - |
dc.subject | MULTICENTER | - |
dc.subject | RECURRENCE | - |
dc.subject | DEATH | - |
dc.subject | TRIAL | - |
dc.title | Ischemic stroke risk during long-term follow up in patients with successful catheter ablation for atrial fibrillation in Korea | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Lee, Kwang-No | - |
dc.contributor.affiliatedAuthor | Shim, Jaemin | - |
dc.contributor.affiliatedAuthor | Choi, Jong-Il | - |
dc.contributor.affiliatedAuthor | Kim, Young-Hoon | - |
dc.identifier.doi | 10.1371/journal.pone.0201061 | - |
dc.identifier.scopusid | 2-s2.0-85050198826 | - |
dc.identifier.wosid | 000439120000085 | - |
dc.identifier.bibliographicCitation | PLOS ONE, v.13, no.7 | - |
dc.relation.isPartOf | PLOS ONE | - |
dc.citation.title | PLOS ONE | - |
dc.citation.volume | 13 | - |
dc.citation.number | 7 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Science & Technology - Other Topics | - |
dc.relation.journalWebOfScienceCategory | Multidisciplinary Sciences | - |
dc.subject.keywordPlus | RADIOFREQUENCY ABLATION | - |
dc.subject.keywordPlus | THROMBOEMBOLIC EVENTS | - |
dc.subject.keywordPlus | ORAL ANTICOAGULATION | - |
dc.subject.keywordPlus | THERAPY | - |
dc.subject.keywordPlus | MULTICENTER | - |
dc.subject.keywordPlus | RECURRENCE | - |
dc.subject.keywordPlus | DEATH | - |
dc.subject.keywordPlus | TRIAL | - |
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