Signal Intensity of Contrast Enhancement according to TE in 3.0T MRI T1 Imaging

Abstract

Normal body tissue or lesion characteristics in T1 images have been evaluated; however, how external parameters effect the change in signal intensity by gadolinium-based contrast agent remains unknown. We investigated how contrast enhancement changed according to echo time (TE) in 3.0T magnetic resonance (MR) T1 imaging and determined the optimal settings for TE in contrast-enhanced T1 imaging. Since there are no guidelines regarding parameters for T1 enhancement when using MR-contrast agents, we analyzed results from varying TEs (between 25 and 7 msec) in both a phantom and clinical study. We obtained the following results: contrast percentage of fat to saline increased from 740.0-1003.6%, response start point increased from 30-90 mmol, max peak signal intensity increased from 1771-2425 a.u., max peak point increased from 2-4 mmol, enhancement percentage of the max peak signal intensity (MPSI) to saline increased from 1671.0-2065.2%, the average of SI on each mol as TE increased from 600.8-996.6 a.u., the average of SI as TE on each molar concentration increased from 378-845 a.u., the AEPSS increased from 44.3-140.3%, and the AEPSC increased from 224.3-647.8%. We confirmed that TE can affect contrast enhancement, and the lowest TE has faster and higher effects on contrast enhancement.