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Disruptions in resting state functional connectivity in euthymic bipolar patients with insomnia symptoms

Authors
Yoon, Ho-KyoungDev, Sheena I.Sutherland, Ashley N.Eyler, Lisa T.
Issue Date
30-5월-2018
Publisher
ELSEVIER IRELAND LTD
Keywords
Bipolar disorder; Insomnia; Resting state
Citation
PSYCHIATRY RESEARCH-NEUROIMAGING, v.275, pp.1 - 4
Indexed
SCIE
SCOPUS
Journal Title
PSYCHIATRY RESEARCH-NEUROIMAGING
Volume
275
Start Page
1
End Page
4
URI
https://scholar.korea.ac.kr/handle/2021.sw.korea/75480
DOI
10.1016/j.pscychresns.2018.03.005
ISSN
0925-4927
Abstract
Insomnia is prevalent in bipolar disorder (BD) even during periods of euthymic mood. We compared resting state brain activity and cognitive function between euthymic BD with and without insomnia, and secondarily to healthy individuals. BD patients with insomnia symptoms showed a significantly lower functional connectivity within the task-positive network, compared to those without insomnia. They also showed significantly slower cognitive processing speed. These two features of BD with insomnia appeared relatively independent of each other. Preliminary findings suggest that exploration of the mechanisms of sleep disturbance in BD could lead to improved understanding and treatment of inattention in BD.
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의과대학 (의학과)
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