High sensitive detection of copper II ions using D-penicillamine-coated gold nanorods based on localized surface plasmon resonance
- Authors
- Hong, Yoochan; Jo, Seongjae; Park, Joohyung; Park, Jinsung; Yang, Jaemoon
- Issue Date
- 25-5월-2018
- Publisher
- IOP PUBLISHING LTD
- Keywords
- localized surface plasmon resonance; copper II ion; D-penicillamine; gold nanorods
- Citation
- NANOTECHNOLOGY, v.29, no.21
- Indexed
- SCIE
SCOPUS
- Journal Title
- NANOTECHNOLOGY
- Volume
- 29
- Number
- 21
- URI
- https://scholar.korea.ac.kr/handle/2021.sw.korea/75494
- DOI
- 10.1088/1361-6528/aab4c4
- ISSN
- 0957-4484
- Abstract
- In this paper, we describe the development of a nanoplasmonic biosensor based on the localized surface plasmon resonance (LSPR) effect that enables a sensitive and selective recognition of copper II ions. First, we fabricated the nanoplasmonics as LSPR substrates using gold nanorods (GNR) and the nano-adsorption method. The LSPR sensitivity of the nanoplasmonics was evaluated using various solvents with different refractive indexes. Subsequently, D-penicillamine ( DPA)-a chelating agent of copper II ions-was conjugated to the surface of the GNR. The limit of detection (LOD) for the DPA-conjugated nanoplasmonics was 100 pM. Furthermore, selectivity tests were conducted using various divalent cations, and sensitivity tests were conducted on the nanoplasmonics under blood-like environments. Finally, the developed nanoplasmonic biosensor based on GNR shows great potential for the effective recognition of copper II ions, even in human blood conditions.
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Collections - Graduate School > Department of Control and Instrumentation Engineering > 1. Journal Articles
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