Protective Effectiveness of Inactivated Hantavirus Vaccine Against Hemorrhagic Fever With Renal Syndrome
- Authors
- Jung, Jaehun; Ko, Sung-Jun; Oh, Hong Sang; Moon, Song Mi; Song, Jin-Won; Huh, Kyungmin
- Issue Date
- 1-5월-2018
- Publisher
- OXFORD UNIV PRESS INC
- Keywords
- hantavirus; vaccine; hemorrhagic fever with renal syndrome
- Citation
- JOURNAL OF INFECTIOUS DISEASES, v.217, no.9, pp.1417 - 1420
- Indexed
- SCIE
SCOPUS
- Journal Title
- JOURNAL OF INFECTIOUS DISEASES
- Volume
- 217
- Number
- 9
- Start Page
- 1417
- End Page
- 1420
- URI
- https://scholar.korea.ac.kr/handle/2021.sw.korea/75586
- DOI
- 10.1093/infdis/jiy037
- ISSN
- 0022-1899
- Abstract
- As there is no effective treatment against hemorrhagic fever with renal syndrome (HFRS), the development of effective vaccine is important. An inactivated hantavirus vaccine (IHV) has been used in Korea, but there has been controversy regarding its effectiveness. We conducted a case-control study to evaluate the vaccine effectiveness (VE) of IHV against HFRS in the Korean military. Unadjusted and adjusted VEs of IHV were 59.1% and 58.9%, respectively. VE was higher in divisions with high incidence of HFRS (unadjusted VE, 71.4%; adjusted VE, 78.7%). Our study demonstrated the moderate effectiveness of IHV in high-risk populations residing in endemic area.
- Files in This Item
- There are no files associated with this item.
- Appears in
Collections - Graduate School > Department of Biomedical Sciences > 1. Journal Articles
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.