Detailed Information

Cited 0 time in webofscience Cited 0 time in scopus
Metadata Downloads

Clinical Efficacy of Solifenacin in the Management of Diabetes Mellitus-Associated Versus Idiopathic Overactive Bladder Symptoms: A Multicenter Prospective Study

Authors
Choi, HoonBae, Jae HyunOh, Cheol YoungJeong, Seong JinKo, Woo JinChoi, Jong BoSeo, Ju TaeLee, Dong HwanKim, Joon ChulLee, Kwang WooKim, Young Ho
Issue Date
3월-2018
Publisher
KOREAN CONTINENCE SOC
Keywords
Anticholinergics; Overactive urinary bladder; Diabetes mellitus
Citation
INTERNATIONAL NEUROUROLOGY JOURNAL, v.22, no.1, pp.51 - 57
Indexed
SCIE
SCOPUS
KCI
Journal Title
INTERNATIONAL NEUROUROLOGY JOURNAL
Volume
22
Number
1
Start Page
51
End Page
57
URI
https://scholar.korea.ac.kr/handle/2021.sw.korea/76814
DOI
10.5213/inj.1834982.491
ISSN
2093-4777
Abstract
Purpose: To compare the clinical efficacy of anticholinergics for managing diabetes mellitus-associated overactive bladder (DM OAB) versus idiopathic overactive bladder (OAB) in Korean women. Methods: We conducted a multicenter, prospective, parallel-group, open-label, 12-week study Women (20-65 years old) with OAB symptoms for over 3 months were assigned to the DM OAB and idiopathic OAB groups, Changes in the Overactive Bladder Symptom Score (OABSS), urgency, urinary urgency incontinence, nocturia, daytime frequency according to a voiding diary, uroflowmetry, and postvoid residual urine volume (PVR) at the first visit (V1), week 4 (V2), and week 12 (V3) were compared. Results: No significant difference was found between the baseline patient characteristics of the DM OAB and idiopathic OAB groups. Treatment with solifenacin was associated with improvements in urgency, urinary urgency incontinence, nocturia, frequency according to a voiding diary, and the total OABSS between V1 and V2 and between VI and V3. Moreover, a significant improvement in urgency and urge incontinence was found between V2 and V3 in the DM OAB group. However, no significant changes were found in any other parameters. There were no significant differences between the DM OAB group and the idiopathic OAB group except for urgency and urge incontinence at V2 (3,71 vs. 2.28 and 0.47 vs, 0,32, respectively). Conclusions: The patients who received solifenacin demonstrated improved urgency, urinary urgency incontinence, nocturia, frequency according to a voiding diary, and total OABSS, Management with solifenacin was equally effective for both DM-related OAB and idiopathic OAB.
Files in This Item
There are no files associated with this item.
Appears in
Collections
College of Medicine > Department of Medical Science > 1. Journal Articles

qrcode

Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.

Related Researcher

Researcher Bae, Jae Hyun photo

Bae, Jae Hyun
의과대학 (의학과)
Read more

Altmetrics

Total Views & Downloads

BROWSE