Terminal Deoxynucleotidyl Transferase-Mediated Deoxyuridine Triphosphate Nick End Labeling (TUNEL) Assay to Characterize Histopathologic Changes Following Thermal Injury
DC Field | Value | Language |
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dc.contributor.author | Lee, Ji Min | - |
dc.contributor.author | Park, Ji Hyun | - |
dc.contributor.author | Kim, Bo Young | - |
dc.contributor.author | Kim, Il-Hwan | - |
dc.date.accessioned | 2021-09-02T15:07:02Z | - |
dc.date.available | 2021-09-02T15:07:02Z | - |
dc.date.created | 2021-06-16 | - |
dc.date.issued | 2018-02 | - |
dc.identifier.issn | 1013-9087 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/77411 | - |
dc.description.abstract | Background: Despite the wide application of lasers and radiofrequency (RF) surgery in dermatology, it is difficult to find studies showing the extent of damage dependent on cell death. Objective: We evaluated histopathologic changes following in vivo thermal damage generated by CO2 laser, 1,444 nm long-pulsed neodymium:yttrium-aluminum-garnet (LP Nd:YAG) laser and RF emitting electrosurgical unit. Methods: Thermal damage was induced by the above instruments on ventral skin of rat. Specimens were stained with hematoxylin and eosin, along with a terminal deoxynucleotidyl transferase-mediated deoxyuridine triphosphate nick end labeling (TUNEL) assay, to highlight the degree of irreversible cellular injury. Results: The volume of vaporization was largest with the CO2 laser. Area of cell death area identified by TUNEL assay, when arranged from widest to narrowest, was 1,444 nm LP Nd:YAG laser, CO2 laser, and RF emitting electrosurgical unit. Conclusion: This histopathologic evaluation of the acute characterization of injury across devices may be advantageous for attaining better treatment outcomes. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | KOREAN DERMATOLOGICAL ASSOC | - |
dc.subject | ALUMINUM-GARNET LASER | - |
dc.subject | NM NDYAG LASER | - |
dc.subject | MONOPOLAR ELECTROSURGERY | - |
dc.subject | MICRODISSECTION ELECTRODES | - |
dc.subject | AXILLARY BROMHIDROSIS | - |
dc.subject | ULTRASONIC SCALPEL | - |
dc.subject | ORAL-MUCOSA | - |
dc.subject | CO2-LASER | - |
dc.subject | RADIOSURGERY | - |
dc.subject | SKIN | - |
dc.title | Terminal Deoxynucleotidyl Transferase-Mediated Deoxyuridine Triphosphate Nick End Labeling (TUNEL) Assay to Characterize Histopathologic Changes Following Thermal Injury | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Kim, Il-Hwan | - |
dc.identifier.doi | 10.5021/ad.2018.30.1.41 | - |
dc.identifier.scopusid | 2-s2.0-85042537462 | - |
dc.identifier.wosid | 000433991800007 | - |
dc.identifier.bibliographicCitation | ANNALS OF DERMATOLOGY, v.30, no.1, pp.41 - 46 | - |
dc.relation.isPartOf | ANNALS OF DERMATOLOGY | - |
dc.citation.title | ANNALS OF DERMATOLOGY | - |
dc.citation.volume | 30 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 41 | - |
dc.citation.endPage | 46 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.identifier.kciid | ART002313373 | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.description.journalRegisteredClass | kci | - |
dc.relation.journalResearchArea | Dermatology | - |
dc.relation.journalWebOfScienceCategory | Dermatology | - |
dc.subject.keywordPlus | ALUMINUM-GARNET LASER | - |
dc.subject.keywordPlus | NM NDYAG LASER | - |
dc.subject.keywordPlus | MONOPOLAR ELECTROSURGERY | - |
dc.subject.keywordPlus | MICRODISSECTION ELECTRODES | - |
dc.subject.keywordPlus | AXILLARY BROMHIDROSIS | - |
dc.subject.keywordPlus | ULTRASONIC SCALPEL | - |
dc.subject.keywordPlus | ORAL-MUCOSA | - |
dc.subject.keywordPlus | CO2-LASER | - |
dc.subject.keywordPlus | RADIOSURGERY | - |
dc.subject.keywordPlus | SKIN | - |
dc.subject.keywordAuthor | Carbon dioxide lasers | - |
dc.subject.keywordAuthor | In situ nick-end labeling | - |
dc.subject.keywordAuthor | Neodymium-doped yttrium aluminum garnet lasers | - |
dc.subject.keywordAuthor | Radiofrequency | - |
dc.subject.keywordAuthor | Thermal destruction | - |
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