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Development of Prediction Equation of Diffusing Capacity of Lung for Koreans

Authors
Il Hwang, YongPark, Yong BumYoon, Hyoung KyuLim, Seong YongKim, Tae-HyungPark, Joo HunLee, Won-YeonPark, Seong JuLee, Sei WonKim, Woo JinKim, Ki UkShin, Kyeong CheolKim, Do JinKim, Hui JungKim, Tae-EunYoo, Kwang HaShim, Jae Jeong
Issue Date
1월-2018
Publisher
TAEHAN KYORHAEK HYOPHOE-KOREAN ACAD TUBERCULOSIS & RESPIRATORY DISEASES
Keywords
Korean; Pulmonary Diffusing Capacity; Diffusion; Carbon Monoxide
Citation
TUBERCULOSIS AND RESPIRATORY DISEASES, v.81, no.1, pp.42 - 48
Indexed
SCOPUS
KCI
Journal Title
TUBERCULOSIS AND RESPIRATORY DISEASES
Volume
81
Number
1
Start Page
42
End Page
48
URI
https://scholar.korea.ac.kr/handle/2021.sw.korea/78054
DOI
10.4046/trd.2017.0118
ISSN
1738-3536
Abstract
Background: The diffusing capacity of the lung is influenced by multiple factors such as age, sex, height, weight, ethnicity and smoking status. Although a prediction equation for the diffusing capacity of Korea was proposed in the mid-1980s, this equation is not used currently. The aim of this study was to develop a new prediction equation for the diffusing capacity for Koreans. Methods: Using the data of the Korean National Health and Nutrition Examination Survey, a total of 140 nonsmokers with normal chest X-rays were enrolled in this study. Results: Using linear regression analysis, a new predicting equation for diffusing capacity was developed. For men, the following new equations were developed: carbon monoxide diffusing capacity (DLco)=-10.4433-0.1434xage (year)+0.2482xheights (cm); DLco/alveolar volume (VA)=6.01507-0.02374xage (year)-0.00233xheights (cm). For women the prediction equations were described as followed: DLco=-12.8895-0.0532xage (year)+ 0.2145xheights (cm) and DLco/VA=7.69516-0.02219xage (year)-0.01377xheights (cm). All equations were internally validated by k-fold cross validation method. Conclusion: In this study, we developed new prediction equations for the diffusing capacity of the lungs of Koreans. A further study is needed to validate the new predicting equation for diffusing capacity.
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