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Nanomaterials and continuous wave laser-based efficient desorption for atmospheric pressure mass spectrometric imaging of live hippocampal tissue slices
- Authors
- Kim, Jae Young; Seo, Eun Seok; Lim, Hee Jin; Kim, Hyunmin; Park, Ji-Won; Shin, Hyeon Ho; Lim, Dong-Kwon; Moon, Dae Won
- Issue Date
- 2018
- Publisher
- ROYAL SOC CHEMISTRY
- Citation
- RSC ADVANCES, v.8, no.15, pp.8021 - 8025
- Indexed
- SCIE
SCOPUS
- Journal Title
- RSC ADVANCES
- Volume
- 8
- Number
- 15
- Start Page
- 8021
- End Page
- 8025
- ISSN
- 2046-2069
- Abstract
- Micrometer-resolution mass spectrometric imaging of live hippocampal tissue is achieved with a highly efficient desorption of biomolecules using a 532 nm continuous wave laser and gold nanoparticles or graphene oxide as an energy transporter, which enables clear identification of the distributions of monoacylglycerol, adenine, cholesterol, sphingosine and ceramide.
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