Change in Weight and Body Mass Index Associated With All- Cause Mortality in Korea: A Nationwide Longitudinal Study
DC Field | Value | Language |
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dc.contributor.author | Kim, Yang-Hyun | - |
dc.contributor.author | Kim, Seon Mee | - |
dc.contributor.author | Han, Kyung-do | - |
dc.contributor.author | Son, Jang-Won | - |
dc.contributor.author | Lee, Seong-Su | - |
dc.contributor.author | Oh, Sang Woo | - |
dc.contributor.author | Lee, Won-Young | - |
dc.contributor.author | Yoo, Soon Jib | - |
dc.date.accessioned | 2021-09-02T23:12:10Z | - |
dc.date.available | 2021-09-02T23:12:10Z | - |
dc.date.created | 2021-06-19 | - |
dc.date.issued | 2017-11-01 | - |
dc.identifier.issn | 0021-972X | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/81603 | - |
dc.description.abstract | Context: Many studies have reported conflicting evidence on the association between weight change and mortality. Objective: We investigated the association between weight change and subsequent all-cause mortality, using a large-scale, population-based cohort from the National Health Insurance System health checkup data between 2005 and 2015. Methods: A total of 11,524,763 subjects older than age 20 years were included. Weight was measured every 2 years and weight change over 4 years was divided into eight categories, from weight loss >= 15% to weight gain >= 20%, for every 5% of weight change. The hazard ratios (HRs) and 95% confidence intervals (CIs) for all-cause mortality were analyzed using multivariable Cox proportional hazard models compared with the stable weight group (weight change >5%) after adjusting for age, sex, smoking, drinking, exercise, diabetes mellitus, hypertension, dyslipidemia, cancer, and income. Results: Weight loss was associated with increased mortality rates compared with weight gain; the group with weight loss >= 15% had the highest HR for all-cause mortality (HR, 2.598; 95% CI, 2.537 to 2.659). The HR for all-cause mortality in the >= 20% weight gain group was 1.784 (95% CI, 1.695 to 1.877). Across all body mass index (BMI) categories, weight loss >= 15% was associated with increased mortality rates and the highest mortality rates were found in the BMI >= 30 kg/m(2) group (HR, 3.469; 95% CI, 2.236 to 5.381). Conclusions: Weight change over 4 years showed a reverse J-shaped all-cause mortality curve, independent of BMI status. Weight loss was associated with a greater risk of mortality than was weight gain. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | ENDOCRINE SOC | - |
dc.subject | ALL-CAUSE MORTALITY | - |
dc.subject | PROSPECTIVE COHORT | - |
dc.subject | US ADULTS | - |
dc.subject | UNITED-STATES | - |
dc.subject | JAPANESE MEN | - |
dc.subject | FOLLOW-UP | - |
dc.subject | WOMEN | - |
dc.subject | AGE | - |
dc.subject | OBESITY | - |
dc.subject | RISK | - |
dc.title | Change in Weight and Body Mass Index Associated With All- Cause Mortality in Korea: A Nationwide Longitudinal Study | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Kim, Yang-Hyun | - |
dc.contributor.affiliatedAuthor | Kim, Seon Mee | - |
dc.identifier.doi | 10.1210/jc.2017-00787 | - |
dc.identifier.wosid | 000414558500018 | - |
dc.identifier.bibliographicCitation | JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, v.102, no.11, pp.4041 - 4050 | - |
dc.relation.isPartOf | JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM | - |
dc.citation.title | JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM | - |
dc.citation.volume | 102 | - |
dc.citation.number | 11 | - |
dc.citation.startPage | 4041 | - |
dc.citation.endPage | 4050 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Endocrinology & Metabolism | - |
dc.relation.journalWebOfScienceCategory | Endocrinology & Metabolism | - |
dc.subject.keywordPlus | ALL-CAUSE MORTALITY | - |
dc.subject.keywordPlus | PROSPECTIVE COHORT | - |
dc.subject.keywordPlus | US ADULTS | - |
dc.subject.keywordPlus | UNITED-STATES | - |
dc.subject.keywordPlus | JAPANESE MEN | - |
dc.subject.keywordPlus | FOLLOW-UP | - |
dc.subject.keywordPlus | WOMEN | - |
dc.subject.keywordPlus | AGE | - |
dc.subject.keywordPlus | OBESITY | - |
dc.subject.keywordPlus | RISK | - |
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