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A facile one-pot regioselective synthesis of functionalized novel benzo[f] chromeno[4,3-b][1,7]naphthyridines and benzo[f][1,7]naphthyridines via an imino Diels-Alder reaction
- Issue Date
- 1-Feb-2017
- Publisher
- PERGAMON-ELSEVIER SCIENCE LTD
- Keywords
- 13H-Benzo[f]chromeno[4,3-b]; [1,7]naphthyridines; 1,3-Diphenylbenzo[f][1,7]naphthyridines; Imino Diels-Alder reaction; Atom economy; One-pot multicomponent reaction
- Citation
- TETRAHEDRON LETTERS, v.58, no.5, pp.449 - 454
- Indexed
- SCIE
SCOPUS
- Journal Title
- TETRAHEDRON LETTERS
- Volume
- 58
- Number
- 5
- Start Page
- 449
- End Page
- 454
- ISSN
- 0040-4039
- Abstract
- A novel series of functionalized 13H-benzo[f]chromeno[4,3-b][1,7]naphthyridines and 1,3-diphenylA-benzo[f][1,7]naphthyridines have been synthesized by an efficient regioselective one -pot multicomponent synthesis through intra and intermolecular imino Diels-Alder reaction. In this method, we have achieved complete regioselectivity and atom economy with polysubstituted core motifs in moderate to good yields. The proposed mechanism of this reaction has also discussed. (C) 2016 Elsevier Ltd. All rights reserved.
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Related Researcher
- Lee, Ki ho
- College of Pharmacy (Department of Pharmaceutical Science)