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Chemical Constituents Isolated from Bletilla striata and Their Inhibitory Effects on Nitric Oxide Production in RAW 264.7 Cells
- Authors
- Bae, Joon Young; Lee, Jin Woo; Jin, Qinghao; Jang, Hari; Lee, Dongho; Kim, Youngsoo; Hong, Jin Tae; Lee, Mi Kyeong; Lee, Moon Soon; Hwang, Bang Yeon
- Issue Date
- 2월-2017
- Publisher
- WILEY-V C H VERLAG GMBH
- Keywords
- Bletilla striata; Orchidaceae; Flavan-3-ol; Nitric oxide production; Bletillanol A; Bletillanol B
- Citation
- CHEMISTRY & BIODIVERSITY, v.14, no.2
- Indexed
- SCIE
SCOPUS
- Journal Title
- CHEMISTRY & BIODIVERSITY
- Volume
- 14
- Number
- 2
- ISSN
- 1612-1872
- Abstract
- Bioassay-guided fractionation of the MeOH extract of the tubers of Bletilla striata led to the isolation of two new C-methylated flavan-3-ols, bletillanols A (1) and B (2), along with ten known compounds (3-12). Their structures were determined by using extensive spectroscopic analysis including 1D-, 2D-NMR, and circular dichroism data. All of the isolated compounds were tested for their inhibitory potential on the nitric oxide generation in LPS-stimulated RAW 264.7 cells.
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Collections - Graduate School > Department of Plant Biotechnology > 1. Journal Articles
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