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만성 비부비동염 환자에서의 비용이 후각장애에 주는 영향The Impact of Nasal Polyposis on Olfactory Dysfunction in Chronic Rhinosinusitis

Other Titles
The Impact of Nasal Polyposis on Olfactory Dysfunction in Chronic Rhinosinusitis
Authors
윤희철김태민주재우송인식홍승노유준혁이승훈
Issue Date
2017
Publisher
대한비과학회
Keywords
Nasal polyp; Rhinosinusitis; Olfaction; 비용·비부비동염·후각
Citation
Journal of Rhinology, v.24, no.1, pp.31 - 36
Indexed
KCI
Journal Title
Journal of Rhinology
Volume
24
Number
1
Start Page
31
End Page
36
URI
https://scholar.korea.ac.kr/handle/2021.sw.korea/85518
DOI
10.18787/jr.2017.24.1.31
ISSN
1229-1498
Abstract
Background and Objectives: Olfactory disturbance is a major sinonasal symptom of chronic rhinosinusitis (CRS) with nasal polyps (NP). The aim of this study was to investigate the relationship between the severity of nasal polyposis and olfactory dysfunction in CRS. Subjects and Method: A total of 277 subjects with CRS were included in this study. All participants were divided into four groups according to the size and degree of the nasal polyposis: the control group (no polyp; n=79); NP (nasal polyp) group I (both or unilateral simple polyposis; n=85); NP group II (unilateral diffuse polyposis; n=66); and NP group III (bilateral diffuse polyposis; n=47). We analyzed the relationships between the severity of nasal polyposis and olfactory dysfunction using both the Korean Version of the “Sniffin’Sticks” test (KVSS Test) II and the Questionnaire of Olfactory Disorders (QOD). Results: The KVSS Test II TDI score was significantly decreased in the bilateral diffuse polyposis group (NP group III= 15.62±13.39) compared to the other polyp groups [control group=25.04±9.67 (p<0.001); NP group I=21.67±11.18 (p=0.005); NP group II=21.51±10.85 (p=0.008)]. However, there were no significant differences in the KVSS Test II TDI score between the control group and NP groups I and II. For the QOD_NS score, only NP group III (11.51±9.87) had significantly increased values compared to the control group [8.42±12.27 (p=0.015)]. Conclusion: These results suggest that bilateral diffuse nasal polyposis is related to significant olfactory dysfunction in CRS.
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