Accelerated Resting-State Functional Magnetic Resonance Imaging Using Multiband Echo-Planar Imaging with Controlled AliasingAccelerated Resting-State Functional Magnetic Resonance Imaging Using Multiband Echo-Planar Imaging with Controlled Aliasing
- Other Titles
- Accelerated Resting-State Functional Magnetic Resonance Imaging Using Multiband Echo-Planar Imaging with Controlled Aliasing
- Authors
- 서형석; 장경은; Dingxin Wang; 김인성; 장용민
- Issue Date
- 2017
- Publisher
- 대한자기공명의과학회
- Keywords
- Multiband EPI; Resting-state fMRI; Resting-state network; Temporal SNR
- Citation
- Investigative Magnetic Resonance Imaging, v.21, no.4, pp.223 - 232
- Indexed
- KCI
- Journal Title
- Investigative Magnetic Resonance Imaging
- Volume
- 21
- Number
- 4
- Start Page
- 223
- End Page
- 232
- URI
- https://scholar.korea.ac.kr/handle/2021.sw.korea/86019
- DOI
- 10.13104/imri.2017.21.4.223
- ISSN
- 2384-1095
- Abstract
- Purpose: To report the use of multiband accelerated echo-planar imaging (EPI) for resting-state functional MRI (rs-fMRI) to achieve rapid high temporal resolution at 3T compared to conventional EPI.
Materials and Methods: rs-fMRI data were acquired from 20 healthy right-handed volunteers by using three methods: conventional single-band gradient-echo EPI acquisition (Data 1), multiband gradient-echo EPI acquisition with 240 volumes (Data 2) and 480 volumes (Data 3). Temporal signal-to-noise ratio (tSNR) maps were obtained by dividing the mean of the time course of each voxel by its temporal standard deviation. The resting-state sensorimotor network (SMN) and default mode network (DMN) were estimated using independent component analysis (ICA) and a seed-based method. One-way analysis of variance (ANOVA) was performed between the tSNR map, SMN, and DMN from the three data sets for between-group analysis.
P < 0.05 with a family-wise error (FWE) correction for multiple comparisons was considered statistically significant.
Results: One-way ANOVA and post-hoc two-sample t-tests showed that the tSNR was higher in Data 1 than Data 2 and 3 in white matter structures such as the striatum and medial and superior longitudinal fasciculus. One-way ANOVA revealed no differences in SMN or DMN across the three data sets.
Conclusion: Within the adapted metrics estimated under specific imaging conditions employed in this study, multiband accelerated EPI, which substantially reduced scan times, provides the same quality image of functional connectivity as rs-fMRI by using conventional EPI at 3T. Under employed imaging conditions, this technique shows strong potential for clinical acceptance and translation of rs-fMRI protocols with potential advantages in spatial and/or temporal resolution. However, further study is warranted to evaluate whether the current findings can be generalized in diverse settings.
- Files in This Item
- There are no files associated with this item.
- Appears in
Collections - College of Medicine > Department of Medical Science > 1. Journal Articles
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.