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Simultaneous patterning of proteins and cells through bioconjugation with photoreactable phospholipid polymers
- Authors
- Seo, Ji-Hun; Ishihara, Kazuhiko
- Issue Date
- 2017
- Publisher
- ROYAL SOC CHEMISTRY
- Citation
- RSC ADVANCES, v.7, no.64, pp.40669 - 40672
- Indexed
- SCIE
SCOPUS
- Journal Title
- RSC ADVANCES
- Volume
- 7
- Number
- 64
- Start Page
- 40669
- End Page
- 40672
- ISSN
- 2046-2069
- Abstract
- Photoreactable bioconjugated macromolecules were synthesized via atom transfer radical polymerization (ATRP), using an N-hydroxysuccinimide ester functional end group with the anti-biofouling 2-methacryloyloxyethyl phosphorylcholine (MPC) units and photoreactable 2-(4-azidobenzamido) ethyl methacrylate units. The polymer was then conjugated with bovine serum albumin (BSA), and the simultaneous patterning of BSA and L-929 fibroblast cells was prepared by a simple coating and irradiation (254 nm UV) process.
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