Molecular and genomic features of Mycobacterium bovis strain 1595 isolated from Korean cattle
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Kim, Narae | - |
dc.contributor.author | Jang, Yunho | - |
dc.contributor.author | Kim, Jin Kyoung | - |
dc.contributor.author | Ryoo, Soyoon | - |
dc.contributor.author | Kwon, Ka Hee | - |
dc.contributor.author | Kim, Miso | - |
dc.contributor.author | Kang, Shin Seok | - |
dc.contributor.author | Byeon, Hyeon Seop | - |
dc.contributor.author | Lee, Hee Soo | - |
dc.contributor.author | Lim, Young-Hee | - |
dc.contributor.author | Kim, Jae-Myung | - |
dc.date.accessioned | 2021-09-03T15:20:58Z | - |
dc.date.available | 2021-09-03T15:20:58Z | - |
dc.date.created | 2021-06-16 | - |
dc.date.issued | 2017 | - |
dc.identifier.issn | 1229-845X | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/86431 | - |
dc.description.abstract | The aim of this study was to investigate the molecular characteristics and to conduct a comparative genomic analysis of Mycobacterium (M.) bovis strain 1595 isolated from a native Korean cow. Molecular typing showed that M. bovis 1595 has spoligotype SB0140 with mycobacterial interspersed repetitive units-variable number of tandem repeats typing of 4-2-5-3-2-7-5-5-4-3-4-3-4-3, representing the most common type of M. bovis in Korea. The complete genome sequence of strain 1595 was determined by single-molecule real-time technology, which showed a genome of 4351712 bp in size with a 65.64% G + C content and 4358 protein-coding genes. Comparative genomic analysis with the genomes of Mycobacterium tuberculosis complex strains revealed that all genomes are similar in size and G + C content. Phylogenetic analysis revealed all strains were within a 0.1% average nucleotide identity value, and MUMmer analysis illustrated that all genomes showed positive collinearity with strain 1595. A sequence comparison based on BLASTP analysis showed that M. bovis AF2122/97 was the strain with the greatest number of completely matched proteins to M. bovis 1595. This genome sequence analysis will serve as a valuable reference for improving understanding of the virulence and epidemiologic traits among M. bovis isolates in Korea. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | KOREAN SOC VETERINARY SCIENCE | - |
dc.subject | TUBERCULOSIS COMPLEX | - |
dc.subject | RNA GENES | - |
dc.subject | ANNOTATION | - |
dc.subject | VIRULENCE | - |
dc.subject | SEQUENCE | - |
dc.subject | DATABASE | - |
dc.subject | TRANSPORT | - |
dc.subject | LIPIDS | - |
dc.title | Molecular and genomic features of Mycobacterium bovis strain 1595 isolated from Korean cattle | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Lim, Young-Hee | - |
dc.identifier.doi | 10.4142/jvs.2017.18.S1.333 | - |
dc.identifier.scopusid | 2-s2.0-85027967850 | - |
dc.identifier.wosid | 000408327300010 | - |
dc.identifier.bibliographicCitation | JOURNAL OF VETERINARY SCIENCE, v.18, pp.333 - 341 | - |
dc.relation.isPartOf | JOURNAL OF VETERINARY SCIENCE | - |
dc.citation.title | JOURNAL OF VETERINARY SCIENCE | - |
dc.citation.volume | 18 | - |
dc.citation.startPage | 333 | - |
dc.citation.endPage | 341 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.description.journalRegisteredClass | kci | - |
dc.relation.journalResearchArea | Veterinary Sciences | - |
dc.relation.journalWebOfScienceCategory | Veterinary Sciences | - |
dc.subject.keywordPlus | TUBERCULOSIS COMPLEX | - |
dc.subject.keywordPlus | RNA GENES | - |
dc.subject.keywordPlus | ANNOTATION | - |
dc.subject.keywordPlus | VIRULENCE | - |
dc.subject.keywordPlus | SEQUENCE | - |
dc.subject.keywordPlus | DATABASE | - |
dc.subject.keywordPlus | TRANSPORT | - |
dc.subject.keywordPlus | LIPIDS | - |
dc.subject.keywordAuthor | Korea | - |
dc.subject.keywordAuthor | Mycobacterium bovis | - |
dc.subject.keywordAuthor | cattle | - |
dc.subject.keywordAuthor | genomics | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
(02841) 서울특별시 성북구 안암로 14502-3290-1114
COPYRIGHT © 2021 Korea University. All Rights Reserved.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.