Effects of BMP-2 Delivery in Calcium Phosphate Bone Graft Materials with Different Compositions on Bone Regeneration
DC Field | Value | Language |
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dc.contributor.author | Park, Jin-Chul | - |
dc.contributor.author | Bae, Eun-Bin | - |
dc.contributor.author | Kim, Se-Eun | - |
dc.contributor.author | Kim, So-Yun | - |
dc.contributor.author | Choi, Kyung-Hee | - |
dc.contributor.author | Choi, Jae-Won | - |
dc.contributor.author | Bae, Ji-Hyeon | - |
dc.contributor.author | Ryu, Jae-Jun | - |
dc.contributor.author | Huh, Jung-Bo | - |
dc.date.accessioned | 2021-09-03T17:20:27Z | - |
dc.date.available | 2021-09-03T17:20:27Z | - |
dc.date.created | 2021-06-16 | - |
dc.date.issued | 2016-11 | - |
dc.identifier.issn | 1996-1944 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/86936 | - |
dc.description.abstract | This study was undertaken to investigate the effect of loading rhBMP-2 onto biphasic calcium phosphate (BCP) and calcium pyrophosphate (CPP) on bone regeneration, and to examine the efficacies of BCP and CPP as rhBMP-2 carriers. Specimens were divided into the BCP, CPP, BCP/BMP, and CPP/BMP groups; BCP and CPP were in granules and not coated with rhBMP-2. BCP/BMP and CPP/BMP were prepared as discs, which were treated with rhBMP-2 and collagen. Physical and biological features were investigated using in-vitro and in-vivo tests. New bone area percentages (%) in the BCP/BMP and CPP/BMP groups were significantly greater than in the BCP and CPP groups. At weeks 4 and 8 post-implantation, CPP/BMP showed the most new bone growth. Within the limitations of this study, treatment of BCP and CPP with rhBMP-2 significantly enhanced bone regeneration. CPP was found to be a suitable carrier for rhBMP-2. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | MDPI AG | - |
dc.subject | MORPHOGENETIC PROTEIN-2 | - |
dc.subject | DENTAL IMPLANTS | - |
dc.subject | HYDROXYAPATITE | - |
dc.subject | AUGMENTATION | - |
dc.subject | SUBSTITUTES | - |
dc.subject | CERAMICS | - |
dc.subject | DEFECTS | - |
dc.subject | RHBMP-2 | - |
dc.subject | TISSUE | - |
dc.subject | PYROPHOSPHATE | - |
dc.title | Effects of BMP-2 Delivery in Calcium Phosphate Bone Graft Materials with Different Compositions on Bone Regeneration | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Ryu, Jae-Jun | - |
dc.identifier.doi | 10.3390/ma9110954 | - |
dc.identifier.scopusid | 2-s2.0-85001976717 | - |
dc.identifier.wosid | 000390114400040 | - |
dc.identifier.bibliographicCitation | MATERIALS, v.9, no.11 | - |
dc.relation.isPartOf | MATERIALS | - |
dc.citation.title | MATERIALS | - |
dc.citation.volume | 9 | - |
dc.citation.number | 11 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Chemistry | - |
dc.relation.journalResearchArea | Materials Science | - |
dc.relation.journalResearchArea | Metallurgy & Metallurgical Engineering | - |
dc.relation.journalResearchArea | Physics | - |
dc.relation.journalWebOfScienceCategory | Chemistry, Physical | - |
dc.relation.journalWebOfScienceCategory | Materials Science, Multidisciplinary | - |
dc.relation.journalWebOfScienceCategory | Metallurgy & Metallurgical Engineering | - |
dc.relation.journalWebOfScienceCategory | Physics, Applied | - |
dc.relation.journalWebOfScienceCategory | Physics, Condensed Matter | - |
dc.subject.keywordPlus | MORPHOGENETIC PROTEIN-2 | - |
dc.subject.keywordPlus | DENTAL IMPLANTS | - |
dc.subject.keywordPlus | HYDROXYAPATITE | - |
dc.subject.keywordPlus | AUGMENTATION | - |
dc.subject.keywordPlus | SUBSTITUTES | - |
dc.subject.keywordPlus | CERAMICS | - |
dc.subject.keywordPlus | DEFECTS | - |
dc.subject.keywordPlus | RHBMP-2 | - |
dc.subject.keywordPlus | TISSUE | - |
dc.subject.keywordPlus | PYROPHOSPHATE | - |
dc.subject.keywordAuthor | alloplast | - |
dc.subject.keywordAuthor | bone substitutes | - |
dc.subject.keywordAuthor | biphasic calcium phosphate | - |
dc.subject.keywordAuthor | calcium pyrophosphate | - |
dc.subject.keywordAuthor | rhBMP-2 | - |
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