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High incidence of group A rotaviruses G4P[6] strains among children in Gyeonggi province of South Korea, from 2009 to 2012

Authors
Mun, Su-KyoungCho, Han-GilLee, Hyun-KyungPark, Sin-HeePark, Po-HyunYoon, Mi-HyeJeong, Hye-SookLim, Young-Hee
Issue Date
Oct-2016
Publisher
ELSEVIER SCIENCE BV
Keywords
Group A rotavirus; Acute gastroenteritis; Genotype; Children
Citation
INFECTION GENETICS AND EVOLUTION, v.44, pp.351 - 355
Indexed
SCIE
SCOPUS
Journal Title
INFECTION GENETICS AND EVOLUTION
Volume
44
Start Page
351
End Page
355
URI
https://scholar.korea.ac.kr/handle/2021.sw.korea/87288
DOI
10.1016/j.meegid.2016.07.038
ISSN
1567-1348
Abstract
The genotype distribution of group A rotaviruses (RVAs) circulating in Gyeonggi province, South Korea between 2009 and 2012 was investigated. A total of 2619 stool specimens from sporadic acute gastroenteritis cases and 117 acute gastroenteritis outbreaks were analyzed. Among them, RVAs were detected from 263 (10.0%) sporadic cases and 3 (2.6%) outbreaks. The G4P[6] strains predominated (29.7%), followed by G1P[8] (19.4%), G2P[4] (15.6%), G3P[8] (13.3%) and G9P[8] (6.5%) strain. Especially 96.2% of the genotype G4P[6] strains were isolated from children < 1 year of age. Phylogenetic analysis revealed that genotype G4P[6] strains were members of sub-lineage Ie(G4) and Ia(P[6]). Intensified monitoring of RVAs, especially G4P[6] strains among young children, is essential to control RVA infections. (C) 2016 Elsevier B.V. All rights reserved.
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