Skin microrelief profiles as a cutaneous aging index
- Authors
- Kim, Dai Hyun; Rhyu, Yeon Seung; Ahn, Hyo Hyun; Hwang, Eenjun; Uhm, Chang Sub
- Issue Date
- 10월-2016
- Publisher
- OXFORD UNIV PRESS
- Keywords
- skin aging; microrelief; silicone replica; scanning electron microscopy; dermoscopy; three-dimensional topography analysis
- Citation
- MICROSCOPY, v.65, no.5, pp.407 - 414
- Indexed
- SCOPUS
- Journal Title
- MICROSCOPY
- Volume
- 65
- Number
- 5
- Start Page
- 407
- End Page
- 414
- URI
- https://scholar.korea.ac.kr/handle/2021.sw.korea/87470
- DOI
- 10.1093/jmicro/dfw019
- ISSN
- 2050-5698
- Abstract
- An objective measurement of cutaneous topographical information is important for quantifying the degree of skin aging. Our aim was to improve methods for measuring microrelief patterns using a three-dimensional analysis based on silicone replicas and scanning electron microscope (SEM). Another objective was to compare the results with those obtained using a two-dimensional analysis method based on dermoscopy. Silicone replicas were obtained from forearms, dorsum of the hands and fingers of 51 volunteers. Cutaneous profiles obtained by SEM with silicone replicas showed more consistent correlations with age than data obtained by dermoscopy. This indicates the advantage of three-dimensional topography analysis using silicone replicas and SEM over the widely used dermoscopic assessment. The cutaneous age was calculated using stepwise linear regression, and the result was 57.40-9.47 x (number of furrows on dorsum of the hand) x (width of furrows on dorsum of the hand).
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- Appears in
Collections - College of Medicine > Department of Medical Science > 1. Journal Articles
- College of Engineering > School of Electrical Engineering > 1. Journal Articles
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