A fluorescent probe for the Fe3+ ion pool in endoplasmic reticulum in liver cells
DC Field | Value | Language |
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dc.contributor.author | Lee, Min Hee | - |
dc.contributor.author | Lee, Hoyeon | - |
dc.contributor.author | Chang, Min Jung | - |
dc.contributor.author | Kim, Hyeong Seok | - |
dc.contributor.author | Kang, Chulhun | - |
dc.contributor.author | Kim, Jong Seung | - |
dc.date.accessioned | 2021-09-03T22:25:22Z | - |
dc.date.available | 2021-09-03T22:25:22Z | - |
dc.date.created | 2021-06-18 | - |
dc.date.issued | 2016-07 | - |
dc.identifier.issn | 0143-7208 | - |
dc.identifier.uri | https://scholar.korea.ac.kr/handle/2021.sw.korea/88209 | - |
dc.description.abstract | We have presented rhodamine-derived Schiff base probes (1-6) selective of the Fe3+ ion in biological systems. In the presence of Fe3+ ions, the probes display new absorption and emission bands at 526 nm and 551 nm, respectively. Confocal microscopic analysis using the HepG2 cell line showed that probes 1-6 provide fluorescence Off-On changes caused by cellular Fe3+ ions, and demonstrated a largely enhanced fluorescence upon iron overloading of the cells. We also found that the Fe3+ ion-mediated fluorescence changes of probes 1-6 are mainly localized in the ER (Endoplasmic Reticulum) in HepG2 cells. Among them, probe 5 exhibits the highest selectivity for ER localization over the other organelles. (C) 2016 Elsevier Ltd. All rights reserved. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | ELSEVIER SCI LTD | - |
dc.subject | MOLECULAR CONTROL | - |
dc.subject | IRON-METABOLISM | - |
dc.title | A fluorescent probe for the Fe3+ ion pool in endoplasmic reticulum in liver cells | - |
dc.type | Article | - |
dc.contributor.affiliatedAuthor | Kim, Jong Seung | - |
dc.identifier.doi | 10.1016/j.dyepig.2016.03.032 | - |
dc.identifier.scopusid | 2-s2.0-84962273783 | - |
dc.identifier.wosid | 000377838700029 | - |
dc.identifier.bibliographicCitation | DYES AND PIGMENTS, v.130, pp.245 - 250 | - |
dc.relation.isPartOf | DYES AND PIGMENTS | - |
dc.citation.title | DYES AND PIGMENTS | - |
dc.citation.volume | 130 | - |
dc.citation.startPage | 245 | - |
dc.citation.endPage | 250 | - |
dc.type.rims | ART | - |
dc.type.docType | Article | - |
dc.description.journalClass | 1 | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.relation.journalResearchArea | Chemistry | - |
dc.relation.journalResearchArea | Engineering | - |
dc.relation.journalResearchArea | Materials Science | - |
dc.relation.journalWebOfScienceCategory | Chemistry, Applied | - |
dc.relation.journalWebOfScienceCategory | Engineering, Chemical | - |
dc.relation.journalWebOfScienceCategory | Materials Science, Textiles | - |
dc.subject.keywordPlus | MOLECULAR CONTROL | - |
dc.subject.keywordPlus | IRON-METABOLISM | - |
dc.subject.keywordAuthor | Iron detection | - |
dc.subject.keywordAuthor | Fluorescent probe | - |
dc.subject.keywordAuthor | Rhodamine | - |
dc.subject.keywordAuthor | Cell imaging | - |
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