Lanostane Triterpenes Isolated from Antrodia heteromorpha and Their Inhibitory Effects on RANKL-Induced Osteoclastogenesis
- Authors
- Kwon, Jaeyoung; Lee, Hyaemin; Yoon, Yeo Dae; Hwang, Bang Yeon; Guo, Yuanqiang; Kang, Jong Soon; Kim, Jae-Jin; Lee, Dongho
- Issue Date
- 6월-2016
- Publisher
- AMER CHEMICAL SOC
- Citation
- JOURNAL OF NATURAL PRODUCTS, v.79, no.6, pp.1689 - 1693
- Indexed
- SCIE
SCOPUS
- Journal Title
- JOURNAL OF NATURAL PRODUCTS
- Volume
- 79
- Number
- 6
- Start Page
- 1689
- End Page
- 1693
- URI
- https://scholar.korea.ac.kr/handle/2021.sw.korea/88464
- DOI
- 10.1021/acs.jnatprod.6b00207
- ISSN
- 0163-3864
- Abstract
- Two new spiro-lanostane triterpenoids, antrolactones A and B (1 and 2), along with polyporenic acid C (3), were isolated from an EtOAc-soluble extract of Antrodia heteromorpha culture medium, and the chemical structures of the new compounds were elucidated by application of NMR, MS, and ECD spectroscopic techniques. All isolated compounds exhibited inhibitory effects on receptor activator of nuclear factor-kappaB ligand-induced osteoclastogenesis.
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Collections - College of Life Sciences and Biotechnology > Division of Environmental Science and Ecological Engineering > 1. Journal Articles
- Graduate School > Department of Plant Biotechnology > 1. Journal Articles
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